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NCT00917462 · ClinicalTrials.gov registry record · Phase 2
Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer
A Phase 2 study of Esophageal Cancer and Gastroesophageal-junction Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT00917462: Completed Phase 2 study of Esophageal Cancer and Gastroesophageal-junction Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT00917462 is a Phase 2 study of Esophageal Cancer and Gastroesophageal-junction Cancer that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 35 participants, below the 499-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00917462, a Phase 2 study of Esophageal Cancer and Gastroesophageal-junction Cancer, has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
Sorafenib is a drug being studied for the treatment of cancer. Sorafenib has been shown to block certain proteins on the surface of some cancer cells called "growth factor receptors." Blocking these growth factor receptors can slow or stop cancer cell growth. Sorafenib is also known as Nexavar®. It has been studied in other types of cancers, including kidney cancer, and has been approved by the Food and Drug Administration (FDA) for treating advanced kidney cancer. Because it is not approved by the FDA for treating esophageal cancer, it is considered an experimental treatment. The purpose of this study is to determine what effects sorafenib has on advanced esophageal cancer. These effects include whether sorafenib can shrink the tumor or slow down its growth and what side effects sorafenib will have on the tumor.
Conditions Studied
Interventions
- DRUG Sorafenib, administered orally
- PROCEDURE CT/MRI
Study Locations (1)
New York
- Memorial Sloan Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2009-06 |
| Est. Completion | 2018-08 |
| Phase | Phase 2 |
What the finished NCT00917462 record still lists
NCT00917462 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 499-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Esophageal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Sorafenib, administered orally is the first listed.
NCT00917462 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT00917462 about?
NCT00917462 is a clinical study titled "Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer". Sorafenib is a drug being studied for the treatment of cancer. Sorafenib has been shown to block certain proteins on the surface of some cancer cells called "growth factor receptors." Blocking these growth factor receptors can slow or stop cancer cell growth. Sorafenib is also known as Nexavar®. It...
What is the current status of trial NCT00917462?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 35 participants. The study started on 2009-06. Estimated completion is 2018-08.
What conditions does trial NCT00917462 study?
This clinical trial studies the following conditions: Esophageal Cancer, Gastroesophageal-junction Cancer.
What interventions are being tested in trial NCT00917462?
The interventions under investigation include: Sorafenib, administered orally (DRUG), CT/MRI (PROCEDURE).
Who is sponsoring clinical trial NCT00917462?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00917462 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00917462's enrollment target sits among peer trials
35 94th of 123 higher than 30 of 123 other Esophageal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Esophageal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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