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NCT00917462 · ClinicalTrials.gov registry record · Phase 2

Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer

A Phase 2 study of Esophageal Cancer and Gastroesophageal-junction Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 2
Development phase
35
Enrollment target
1
Study location

NCT00917462 is a Phase 2 study of Esophageal Cancer and Gastroesophageal-junction Cancer that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 35 participants, below the 499-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00917462, a Phase 2 study of Esophageal Cancer and Gastroesophageal-junction Cancer, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
35 participants
Enrollment target
1
Study location

Study Summary

Sorafenib is a drug being studied for the treatment of cancer. Sorafenib has been shown to block certain proteins on the surface of some cancer cells called "growth factor receptors." Blocking these growth factor receptors can slow or stop cancer cell growth. Sorafenib is also known as Nexavar®. It has been studied in other types of cancers, including kidney cancer, and has been approved by the Food and Drug Administration (FDA) for treating advanced kidney cancer. Because it is not approved by the FDA for treating esophageal cancer, it is considered an experimental treatment. The purpose of this study is to determine what effects sorafenib has on advanced esophageal cancer. These effects include whether sorafenib can shrink the tumor or slow down its growth and what side effects sorafenib will have on the tumor.

Interventions

  • DRUG Sorafenib, administered orally
  • PROCEDURE CT/MRI

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2009-06
Est. Completion 2018-08
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT00917462

The ClinicalTrials.gov registry entry for NCT00917462 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 499-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (93% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Esophageal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Sorafenib, administered orally is the first listed.

NCT00917462 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT00917462 about?

NCT00917462 is a clinical study titled "Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer". Sorafenib is a drug being studied for the treatment of cancer. Sorafenib has been shown to block certain proteins on the surface of some cancer cells called "growth factor receptors." Blocking these growth factor receptors can slow or stop cancer cell growth. Sorafenib is also known as Nexavar®. It...

What is the current status of trial NCT00917462?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 35 participants. The study started on 2009-06. Estimated completion is 2018-08.

What conditions does trial NCT00917462 study?

This clinical trial studies the following conditions: Esophageal Cancer, Gastroesophageal-junction Cancer.

What interventions are being tested in trial NCT00917462?

The interventions under investigation include: Sorafenib, administered orally (DRUG), CT/MRI (PROCEDURE).

Who is sponsoring clinical trial NCT00917462?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00917462 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.