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NCT00896389 · ClinicalTrials.gov registry record · Phase 4
Salt Loading and Thiazide Intervention Study
A Phase 4 study of Hypertension, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- Phase 4
- Development phase
- 124
- Enrollment target
- 1
- Study location
NCT00896389: Completed Phase 4 study of Hypertension, sponsored by University of Maryland, Baltimore.
NCT00896389 is a Phase 4 study of Hypertension that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 124 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00896389, a Phase 4 study of Hypertension, has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 124 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators of this study propose to examine the relationships between STK39 (Serine Threonine Kinase 39) genotypes and responses to salt loading and to thiazide diuretics, hydrochlorothiazide. The investigators hypothesize that STK39 genotypes will be associated with the outcome of both interventions and can contribute to personalized care for hypertension.
Primary Outcome
Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured every 15 minutes for 4 hours. Blood pressure change is calculated by the trapezoid method. Essentially we use the average of blood pressure at each pair of time points (for example, DBP 30min + DBP 15min)/2 + (DBP 45min + DBP 30min)/2 + … up to 4 hours.) normalized by baseline SBP/DBP.
Conditions Studied
Interventions
- PROCEDURE Salt loading
- DRUG Hydrochlorothiazide (HCTZ)
Study Locations (1)
Pennsylvania
- Amish Research Clinics - Lancaster
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 124 participants |
| Start Date | 2009-10 |
| Est. Completion | 2013-03 |
| Phase | Phase 4 |
What the finished NCT00896389 record still lists
NCT00896389 is an interventional study that assigns participants to a tested intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Salt loading is the first listed.
NCT00896389 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00896389 about?
NCT00896389 is a clinical study titled "Salt Loading and Thiazide Intervention Study". The investigators of this study propose to examine the relationships between STK39 (Serine Threonine Kinase 39) genotypes and responses to salt loading and to thiazide diuretics, hydrochlorothiazide. The investigators hypothesize that STK39 genotypes will be associated with the outcome of both inter...
What is the current status of trial NCT00896389?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 124 participants. The study started on 2009-10. Estimated completion is 2013-03.
What conditions does trial NCT00896389 study?
This clinical trial studies the following conditions: Hypertension.
What interventions are being tested in trial NCT00896389?
The interventions under investigation include: Salt loading (PROCEDURE), Hydrochlorothiazide (HCTZ) (DRUG).
Who is sponsoring clinical trial NCT00896389?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00896389 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00896389's enrollment target sits among peer trials
124 265th of 470 higher than 206 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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