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NCT00850018 · ClinicalTrials.gov registry record · Phase 1
Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study
A Phase 1 study of Anemia, Sickle Cell, sponsored by UCSF Benioff Children's Hospital Oakland.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
- 14
- Study locations
NCT00850018: Completed Phase 1 study of Anemia, Sickle Cell, sponsored by UCSF Benioff Children's Hospital Oakland.
NCT00850018 is a Phase 1 study of Anemia, Sickle Cell that has completed, run by UCSF Benioff Children's Hospital Oakland. The registered enrollment target is 36 participants, below the 116-participant average among 17 other Anemia, Sickle Cell trials with a reported enrollment target (69% lower). The trial reports 14 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00850018, a Phase 1 study of Anemia, Sickle Cell, has completed, sponsored by UCSF Benioff Children's Hospital Oakland.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
- 14
- Study locations
Study Summary
Sickle cell disease (SCD), also known as sickle cell anemia, is an inherited blood disease that can cause intense pain episodes and may lead to organ failure. Preliminary studies have shown that adults with SCD may have brain abnormalities that contribute to problems with cognitive functioning, including attention and memory difficulties. This study will use brain magnetic resonance imaging (MRI) and neuropsychological testing to examine the differences in cognitive functioning in adults with SCD who are treated for anemia with monthly blood transfusions for 6 months versus adults with SCD who receive usual care for 6 months.
Conditions Studied
Interventions
- BEHAVIORAL Usual care
- PROCEDURE Monthly blood transfusion regimen
Study Locations (14)
Florida
- Memorial Cancer Institute - Hollywood
- University of Miami Miller School of Medicine - Miami
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
- Duke University Medical Center - Durham
Ohio
- Cincinnati Children's Hospital - Cincinnati
- University of Cincinnati Medical Center - Cincinnati
California
- Children's Hospital & Research Center at Oakland - Oakland
District of Columbia
- Howard University - Washington D.C.
Georgia
- Medical College of Georgia - Augusta
Maryland
- Johns Hopkins - Baltimore
Massachusetts
- Boston Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2004-12 |
| Est. Completion | 2010-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00850018
The ClinicalTrials.gov registry entry for NCT00850018 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 116-participant average among 17 other Anemia, Sickle Cell trials with a reported enrollment target (69% lower). The listed sponsor is UCSF Benioff Children's Hospital Oakland, which has 52 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Anemia, Sickle Cell appearing as the primary indexed condition, and to 2 interventions - of which Usual care is the first listed.
NCT00850018 reports 14 study locations spanning 11 distinct geographic areas - top geographies include Florida, North Carolina, Ohio.
Frequently Asked Questions
What is clinical trial NCT00850018 about?
NCT00850018 is a clinical study titled "Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study". Sickle cell disease (SCD), also known as sickle cell anemia, is an inherited blood disease that can cause intense pain episodes and may lead to organ failure. Preliminary studies have shown that adults with SCD may have brain abnormalities that contribute to problems with cognitive functioning, incl...
What is the current status of trial NCT00850018?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2004-12. Estimated completion is 2010-12.
What conditions does trial NCT00850018 study?
This clinical trial studies the following conditions: Anemia, Sickle Cell.
What interventions are being tested in trial NCT00850018?
The interventions under investigation include: Usual care (BEHAVIORAL), Monthly blood transfusion regimen (PROCEDURE).
Who is sponsoring clinical trial NCT00850018?
This trial is sponsored by UCSF Benioff Children's Hospital Oakland, which has 52 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00850018 being conducted?
This trial has 14 study locations across California, District of Columbia, Florida, Georgia, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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