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NCT00765804 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye
A Phase 2 study of Dry Eye Syndrome, sponsored by Eyegate Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 89
- Enrollment target
- 2
- Study locations
NCT00765804: Completed Phase 2 study of Dry Eye Syndrome, sponsored by Eyegate Pharmaceuticals.
NCT00765804 is a Phase 2 study of Dry Eye Syndrome that has completed, run by Eyegate Pharmaceuticals. The registered enrollment target is 89 participants, below the 156-participant average among 10 other Dry Eye Syndrome trials with a reported enrollment target (43% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00765804, a Phase 2 study of Dry Eye Syndrome, has completed, sponsored by Eyegate Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 89 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to assess the safety and efficacy of iontophoretic delivery of dexamethasone phosphate ophthalmic solution using the EyeGate® II Drug Delivery System in patients with dry eye.
Primary Outcome
Corneal fluorescein staining after CAE exposure at Visit 5 as measured by the ORA scale.
Conditions Studied
Interventions
- DRUG EGP-437 with EyeGate® II System
- DRUG Sodium citrate buffer solution with EyeGate® II System
Study Locations (2)
Massachusetts
- Ophthalmic Research Associates - Andover
- Ophthalmic Research Associates - North Andover
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 89 participants |
| Start Date | 2008-10 |
| Est. Completion | 2009-02 |
| Phase | Phase 2 |
What the finished NCT00765804 record still lists
NCT00765804 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 89 participants, a relatively small participant target, below the 156-participant average among 10 other Dry Eye Syndrome trials with a reported enrollment target (43% lower).
The record links to 1 condition, with Dry Eye Syndrome appearing as the primary indexed condition, and to 2 interventions - of which EGP-437 with EyeGate® II System is the first listed.
NCT00765804 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00765804 about?
NCT00765804 is a clinical study titled "Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye". The purpose of this study is to assess the safety and efficacy of iontophoretic delivery of dexamethasone phosphate ophthalmic solution using the EyeGate® II Drug Delivery System in patients with dry eye.
What is the current status of trial NCT00765804?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 89 participants. The study started on 2008-10. Estimated completion is 2009-02.
What conditions does trial NCT00765804 study?
This clinical trial studies the following conditions: Dry Eye Syndrome.
What interventions are being tested in trial NCT00765804?
The interventions under investigation include: EGP-437 with EyeGate® II System (DRUG), Sodium citrate buffer solution with EyeGate® II System (DRUG).
Who is sponsoring clinical trial NCT00765804?
This trial is sponsored by Eyegate Pharmaceuticals, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00765804 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dry Eye Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00765804's enrollment target sits among peer trials
89 4th of 10 higher than 6 of 10 other Dry Eye Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dry Eye Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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