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NCT01797822 · ClinicalTrials.gov registry record · Phase 4
Effects of Dry Eye Treatments on the Ocular Surface
A Phase 4 study of Dry Eye Syndrome and Keratoconjunctivitis Sicca, sponsored by Baylor College of Medicine.
- Completed
- Registry status
- Phase 4
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT01797822: Completed Phase 4 study of Dry Eye Syndrome and Keratoconjunctivitis Sicca, sponsored by Baylor College of Medicine.
NCT01797822 is a Phase 4 study of Dry Eye Syndrome and Keratoconjunctivitis Sicca that has completed, run by Baylor College of Medicine. The registered enrollment target is 20 participants, below the 163-participant average among 10 other Dry Eye Syndrome trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01797822, a Phase 4 study of Dry Eye Syndrome and Keratoconjunctivitis Sicca, has completed, sponsored by Baylor College of Medicine.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate whether, in people with dry eye syndrome, over the counter artificial tears and the prescription eye drop, dexamethasone, change or effect the eyes response to a low humidity environment. It is known that irritation from dry eye can be improved by over the counter artificial tears because they wet and lubricate the eyes. The prescription eye drop, dexamethasone, can also improve eye irritation by decreasing the inflammation that develops in dry eye. Thus, the investigators hypothesize that the use of these conventional dry eye treatments will improve the eyes' response to a low humidity environment.
Primary Outcome
Subjects will be treated with preservative-free artificial tears for 2 weeks then exposed to a low humidity environment for 90 minutes, then treated with preservative-free dexamethasone 0.1% for 2 weeks and exposed to a low humidity environment again. The change in corneal fluorescein staining before and after the low humidity exposure was measured after each treatment. Fluorescein staining was graded using the CCLR scale (0-100) in 5 zones on the cornea for a maximum score of 500 (range 0-500).
Conditions Studied
Interventions
- DRUG Dexamethasone
- DRUG Artificial tear
Study Locations (1)
Texas
- Baylor College of Medicine, Alkek Eye Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2013-02 |
| Est. Completion | 2015-12 |
| Phase | Phase 4 |
What the finished NCT01797822 record still lists
NCT01797822 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 163-participant average among 10 other Dry Eye Syndrome trials with a reported enrollment target (88% lower).
The record links to 2 conditions, with Dry Eye Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Dexamethasone is the first listed.
NCT01797822 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT01797822 about?
NCT01797822 is a clinical study titled "Effects of Dry Eye Treatments on the Ocular Surface". The purpose of this study is to evaluate whether, in people with dry eye syndrome, over the counter artificial tears and the prescription eye drop, dexamethasone, change or effect the eyes response to a low humidity environment. It is known that irritation from dry eye can be improved by over the c...
What is the current status of trial NCT01797822?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2013-02. Estimated completion is 2015-12.
What conditions does trial NCT01797822 study?
This clinical trial studies the following conditions: Dry Eye Syndrome, Keratoconjunctivitis Sicca.
What interventions are being tested in trial NCT01797822?
The interventions under investigation include: Dexamethasone (DRUG), Artificial tear (DRUG).
Who is sponsoring clinical trial NCT01797822?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01797822 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dry Eye Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01797822's enrollment target sits among peer trials
20 10th of 10 the lowest of 10 other Dry Eye Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dry Eye Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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