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Dry Eye Syndrome clinical trials
Every US clinical trial registered for Dry Eye Syndrome — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
11 US clinical trials · 1 currently recruiting
The research picture
Dry Eye Syndrome has 11 registered US clinical trials, 1 of them open to new participants right now — about 9% of the total.
- 1
- recruiting participants now
- 9%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Mitotech
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE) and Sjogren's Disease (SjD)
AbbVie
NCT06977724
Vehicle-Controlled Study of SkQ1 as Treatment for Dry-eye Syndrome
Mitotech
NCT04206020
Study of SkQ1 as Treatment for Dry-eye Syndrome
Mitotech
NCT03764735
Safety and Efficacy of BRM421 for Dry Eye Syndrome Treatment
BRIM Biotechnology
NCT04343287
Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye
Eyegate Pharmaceuticals
NCT00765804
Safety, PK and Efficacy Study of SJP-0132 in Subjects With Dry Eye Disease
Senju Pharmaceutical Co.
NCT04139122
Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator
Oculeve
NCT02798289
Study of ST266 Eye Drops in Treating Dry Eye
Noveome Biotherapeutics, formerly Stemnion
NCT02369861
Oral Omega-3 Fatty Acids in the Treatment of Dry Eye Syndrome
Milton S. Hershey Medical Center
NCT01107964
Effects of Dry Eye Treatments on the Ocular Surface
Baylor College of Medicine
NCT01797822
The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability
Southern California College of Optometry at Marshall B. Ketchum University
NCT01013077
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 2 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dry Eye Syndrome Trial Landscape
ClinicalTrials.gov lists 11 US studies indexed under Dry Eye Syndrome, and 1 of those are currently open to recruitment — roughly 9% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Dry Eye Syndrome shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Dry Eye Syndrome is led by Mitotech with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 11 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dry Eye Syndrome?
PlainTrial tracks 11 US clinical trials for Dry Eye Syndrome, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dry Eye Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.