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NCT05837845 · ClinicalTrials.gov registry record · Phase 2

MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder

A Phase 2 study of PTSD, sponsored by Patricia Suppes.

Recruiting
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT05837845 is a Phase 2 study of PTSD that is actively recruiting participants, run by Patricia Suppes. The registered enrollment target is 30 participants, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05837845, a Phase 2 study of PTSD, is actively recruiting participants, sponsored by Patricia Suppes.

RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

In partnership with the Veterans Affairs (VA) Palo Alto Health Care System and Stanford University, this study aims to evaluate clinical outcomes, assess implementation feasibility, and health economics of MDMA-assisted Cognitive Processing Therapy (MDMA-aCPT) in the treatment of posttraumatic stress disorder (PTSD). Through a randomized comparison of MDMA-aCPT versus Cognitive Processing Therapy (CPT), a VA gold standard treatment for PTSD, the proposed study will set the stage for understanding the potential use and application of MDMA-aCPT for PTSD within the VA system.

Conditions Studied

Interventions

  • BEHAVIORAL Cognitive Processing Therapy
  • DRUG MDMA
  • BEHAVIORAL MDMA-assisted Cognitive Processing Therapy (MDMA-aCPT)

Study Locations (1)

California

  • VA Palo Alto Health Care System / Stanford University - Palo Alto

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-02-10
Est. Completion 2027-12
Phase Phase 2

Sponsor

Patricia Suppes

1 total trials

What the Registry Record Tells You About NCT05837845

The ClinicalTrials.gov registry entry for NCT05837845 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (90% lower). The listed sponsor is Patricia Suppes, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with PTSD appearing as the primary indexed condition, and to 3 interventions - of which Cognitive Processing Therapy is the first listed.

NCT05837845 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05837845 about?

NCT05837845 is a clinical study titled "MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder". In partnership with the Veterans Affairs (VA) Palo Alto Health Care System and Stanford University, this study aims to evaluate clinical outcomes, assess implementation feasibility, and health economics of MDMA-assisted Cognitive Processing Therapy (MDMA-aCPT) in the treatment of posttraumatic stres...

What is the current status of trial NCT05837845?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2025-02-10. Estimated completion is 2027-12.

What conditions does trial NCT05837845 study?

This clinical trial studies the following conditions: PTSD.

What interventions are being tested in trial NCT05837845?

The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL), MDMA (DRUG), MDMA-assisted Cognitive Processing Therapy (MDMA-aCPT) (BEHAVIORAL).

Who is sponsoring clinical trial NCT05837845?

This trial is sponsored by Patricia Suppes, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05837845 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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