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NCT00516165 · ClinicalTrials.gov registry record · Phase 1

RAD001 in Advanced Hepatocellular Carcinoma

A Phase 1 study of Hepatocellular Carcinoma, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 1
Development phase
28
Enrollment target
3
Study locations

NCT00516165 is a Phase 1 study of Hepatocellular Carcinoma that has completed, run by Massachusetts General Hospital. The registered enrollment target is 28 participants, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (89% lower). The trial reports 3 study locations across 1 state.

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The verdict

NCT00516165, a Phase 1 study of Hepatocellular Carcinoma, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 1
Development phase
28 participants
Enrollment target
3
Study locations

Study Summary

Laboratory studies have shown that RAD001 can prevent cells from multiplying. Consequently, the study drug is being tested in medical conditions in which excessive cell multiplication (as in cancer) needs to be stopped. The main purpose of this research study is to find the highest dose of RAD001 that can be given safely (without causing severe side effects) and to learn the effects (good or bad) RAD001 has on participants with liver cancer.

Conditions Studied

Interventions

  • DRUG RAD001

Study Locations (3)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Dana-Farber Cancer Institute - Boston
  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2007-08
Est. Completion 2011-11
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT00516165

The ClinicalTrials.gov registry entry for NCT00516165 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (89% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hepatocellular Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which RAD001 is the first listed.

NCT00516165 reports 3 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00516165 about?

NCT00516165 is a clinical study titled "RAD001 in Advanced Hepatocellular Carcinoma". Laboratory studies have shown that RAD001 can prevent cells from multiplying. Consequently, the study drug is being tested in medical conditions in which excessive cell multiplication (as in cancer) needs to be stopped. The main purpose of this research study is to find the highest dose of RAD001 th...

What is the current status of trial NCT00516165?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2007-08. Estimated completion is 2011-11.

What conditions does trial NCT00516165 study?

This clinical trial studies the following conditions: Hepatocellular Carcinoma.

What interventions are being tested in trial NCT00516165?

The interventions under investigation include: RAD001 (DRUG).

Who is sponsoring clinical trial NCT00516165?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00516165 being conducted?

This trial has 3 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.