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NCT06710223 · ClinicalTrials.gov registry record · Phase 1
Cryoablation and Arterial Infusion of SD-101 in Combination with Durvalumab and Tremelimumab
A Phase 1 study of Hepatocellular Carcinoma, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06710223 is a Phase 1 study of Hepatocellular Carcinoma that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 20 participants, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06710223, a Phase 1 study of Hepatocellular Carcinoma, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this Phase 1b clinical trial is to evaluate the safety and efficacy of cryoablation and hepatic arterial administration of SD-101 in participants with advanced hepatocellular carcinoma. After this procedure, participants will be treated with tremelimumab and durvalumab every 4 weeks (STRIDE regimen).
Conditions Studied
Interventions
- DRUG Durvalumab
- DRUG Tremelimumab
- DRUG SD-101
- DEVICE Cryotherapy
Study Locations (1)
California
- University of California, San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-01-03 |
| Est. Completion | 2027-06 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06710223
The ClinicalTrials.gov registry entry for NCT06710223 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (92% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hepatocellular Carcinoma appearing as the primary indexed condition, and to 4 interventions - of which Durvalumab is the first listed.
NCT06710223 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT06710223 about?
NCT06710223 is a clinical study titled "Cryoablation and Arterial Infusion of SD-101 in Combination with Durvalumab and Tremelimumab". The goal of this Phase 1b clinical trial is to evaluate the safety and efficacy of cryoablation and hepatic arterial administration of SD-101 in participants with advanced hepatocellular carcinoma. After this procedure, participants will be treated with tremelimumab and durvalumab every 4 weeks (STR...
What is the current status of trial NCT06710223?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2025-01-03. Estimated completion is 2027-06.
What conditions does trial NCT06710223 study?
This clinical trial studies the following conditions: Hepatocellular Carcinoma.
What interventions are being tested in trial NCT06710223?
The interventions under investigation include: Durvalumab (DRUG), Tremelimumab (DRUG), SD-101 (DRUG), Cryotherapy (DEVICE).
Who is sponsoring clinical trial NCT06710223?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06710223 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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