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NCT00452218 · ClinicalTrials.gov registry record · Phase 1

Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH)

A Phase 1 study of Pulmonary Arterial Hypertension, sponsored by University of Chicago.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT00452218 is a Phase 1 study of Pulmonary Arterial Hypertension that has completed, run by University of Chicago. The registered enrollment target is 12 participants, below the 462-participant average among 63 other Pulmonary Arterial Hypertension trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00452218, a Phase 1 study of Pulmonary Arterial Hypertension, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess the safety and tolerability of sorafenib in patients with PAH already on existing therapy with a prostacyclin \[epoprostenol (Flolan)\], treprostinil (Remodulin), or iloprost alone, or with or without sildenafil (Viagra/Revatio).

Interventions

  • DRUG Sorafenib

Study Locations (1)

Illinois

  • The University of Chicago - Chicago

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2007-03
Est. Completion 2012-05
Phase Phase 1

Sponsor

University of Chicago

796 total trials

What the Registry Record Tells You About NCT00452218

The ClinicalTrials.gov registry entry for NCT00452218 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 462-participant average among 63 other Pulmonary Arterial Hypertension trials with a reported enrollment target (97% lower). The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pulmonary Arterial Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Sorafenib is the first listed.

NCT00452218 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT00452218 about?

NCT00452218 is a clinical study titled "Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH)". The purpose of this study is to assess the safety and tolerability of sorafenib in patients with PAH already on existing therapy with a prostacyclin \[epoprostenol (Flolan)\], treprostinil (Remodulin), or iloprost alone, or with or without sildenafil (Viagra/Revatio).

What is the current status of trial NCT00452218?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2007-03. Estimated completion is 2012-05.

What conditions does trial NCT00452218 study?

This clinical trial studies the following conditions: Pulmonary Arterial Hypertension.

What interventions are being tested in trial NCT00452218?

The interventions under investigation include: Sorafenib (DRUG).

Who is sponsoring clinical trial NCT00452218?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00452218 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.