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NCT00452218 · ClinicalTrials.gov registry record · Phase 1
Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH)
A Phase 1 study of Pulmonary Arterial Hypertension, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT00452218: Completed Phase 1 study of Pulmonary Arterial Hypertension, sponsored by University of Chicago.
NCT00452218 is a Phase 1 study of Pulmonary Arterial Hypertension that has completed, run by University of Chicago. The registered enrollment target is 12 participants, below the 462-participant average among 63 other Pulmonary Arterial Hypertension trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00452218, a Phase 1 study of Pulmonary Arterial Hypertension, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to assess the safety and tolerability of sorafenib in patients with PAH already on existing therapy with a prostacyclin \[epoprostenol (Flolan)\], treprostinil (Remodulin), or iloprost alone, or with or without sildenafil (Viagra/Revatio).
Conditions Studied
Interventions
- DRUG Sorafenib
Study Locations (1)
Illinois
- The University of Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2007-03 |
| Est. Completion | 2012-05 |
| Phase | Phase 1 |
What the finished NCT00452218 record still lists
NCT00452218 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 462-participant average among 63 other Pulmonary Arterial Hypertension trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Pulmonary Arterial Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Sorafenib is the first listed.
NCT00452218 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT00452218 about?
NCT00452218 is a clinical study titled "Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH)". The purpose of this study is to assess the safety and tolerability of sorafenib in patients with PAH already on existing therapy with a prostacyclin \[epoprostenol (Flolan)\], treprostinil (Remodulin), or iloprost alone, or with or without sildenafil (Viagra/Revatio).
What is the current status of trial NCT00452218?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2007-03. Estimated completion is 2012-05.
What conditions does trial NCT00452218 study?
This clinical trial studies the following conditions: Pulmonary Arterial Hypertension.
What interventions are being tested in trial NCT00452218?
The interventions under investigation include: Sorafenib (DRUG).
Who is sponsoring clinical trial NCT00452218?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00452218 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00452218's enrollment target sits among peer trials
12 57th of 63 higher than 6 of 63 other Pulmonary Arterial Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pulmonary Arterial Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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