Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00353652 · ClinicalTrials.gov registry record · Phase 4

Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension

A Phase 4 study of Hypertension, sponsored by University of Texas Southwestern Medical Center.

Completed
Registry status
Phase 4
Development phase
166
Enrollment target
2
Study locations

NCT00353652 is a Phase 4 study of Hypertension that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 166 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00353652, a Phase 4 study of Hypertension, has completed, sponsored by University of Texas Southwestern Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
166 participants
Enrollment target
2
Study locations

Study Summary

Thiazide medications are often prescribed for individuals with high blood pressure, but research has shown that they may increase an individual's risk of developing diabetes. While it is unknown exactly how thiazide causes this response, it is likely that the nervous system is somehow involved. This study will evaluate the role of the nervous system in sugar metabolism, as well as determine the effect of thiazide and other medications on individuals with high blood pressure.

Conditions Studied

Hypertension

Interventions

  • DRUG Study#1: chlorthalidone (CTD), titrated dose
  • DRUG Study #1: spironolactone (SP), titrated dose
  • DRUG Study# 2 chlorthalidone (CTD), fixed dose
  • DRUG Study# 2 spironolactone (SP), fixed dose
  • DRUG Study# 2 irbsesartan (IR), fixed dose

Study Locations (2)

Texas

  • University of Texas Southwestern Medical Center at Dallas - Dallas
  • University of Texas Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 166 participants
Start Date 2005-01
Est. Completion 2013-01
Phase Phase 4

Sponsor

University of Texas Southwestern Medical Center

837 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00353652

The ClinicalTrials.gov registry entry for NCT00353652 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 166 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (95% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 5 interventions - of which Study#1: chlorthalidone (CTD), titrated dose is the first listed.

NCT00353652 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT00353652 about?

NCT00353652 is a clinical study titled "Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension". Thiazide medications are often prescribed for individuals with high blood pressure, but research has shown that they may increase an individual's risk of developing diabetes. While it is unknown exactly how thiazide causes this response, it is likely that the nervous system is somehow involved. This...

What is the current status of trial NCT00353652?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 166 participants. The study started on 2005-01. Estimated completion is 2013-01.

What conditions does trial NCT00353652 study?

This clinical trial studies the following conditions: Hypertension.

What interventions are being tested in trial NCT00353652?

The interventions under investigation include: Study#1: chlorthalidone (CTD), titrated dose (DRUG), Study #1: spironolactone (SP), titrated dose (DRUG), Study# 2 chlorthalidone (CTD), fixed dose (DRUG), Study# 2 spironolactone (SP), fixed dose (DRUG), Study# 2 irbsesartan (IR), fixed dose (DRUG).

Who is sponsoring clinical trial NCT00353652?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00353652 being conducted?

This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Hypertension

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Hypertension

All registered trials for this condition

Texas

All trials with a study site in Texas

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.