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COMPLETED Phase 2

Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)

NCT00326339 · View on ClinicalTrials.gov ↗

Study Summary

This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, ascending dose, dose ranging study to evaluate up to three doses of R935788 (50 mg bid, 100 mg bid and 150 mg bid). Approximately 180 patients who have had rheumatoid arthritis for a minimum of 12 months and who have been receiving a weekly methotrexate (MTX) dose for a minimum of 6 months will be enrolled into the study.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG R788

Study Locations (20)

Florida

  • DMI research — Ocala
  • Renstar Medical Research — Ocala
  • Arthritis & Osteoporosis Treatment Center — Orange Park
  • Arthritis Associates Inc. — Orlando
  • Arthritis Research of Florida, Inc. — Palm Harbor
  • Arthritis Research of Florida — Palm Harbor
  • Lovelace Scientific Resources — Sarasota
  • The Center for Arthritis and Rheumatic Diseas — South Miami

Pennsylvania

  • East Penn Rheumatology Associates — Bethlehem
  • Altoona Ctr. for Clinical Research — Duncansville

California

  • Pacific Arthritis Center Medical Group — Santa Maria

Idaho

  • Coeur d'Alene Arthritis Clinical Trials — Coeur d'Alene

Illinois

  • The Arthritis Center — Springfield

Indiana

  • MMG Clinical Research — South Bend

Massachusetts

  • Phase III Clinical Research — Fall River

Michigan

  • Michigan Arthritis Research Center — Brighton

Trial Details

FieldValue
Enrollment Target 189 participants
Start Date 2006-08
Est. Completion 2007-12
Phase Phase 2

Sponsor

Rigel Pharmaceuticals

68 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00326339

The ClinicalTrials.gov registry entry for NCT00326339 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 189 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rigel Pharmaceuticals, which has 68 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00326339 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, Pennsylvania, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00326339 about?

NCT00326339 is a clinical study titled "Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)". This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, ascending dose, dose ranging study to evaluate up to three doses of R935788 (50 mg bid, 100 mg bid and 150 mg bid). Approximately 180 patients who have had rheumatoid arthritis for a minimum of 12 months and who have been...

What is the current status of trial NCT00326339?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 189 participants. The study started on 2006-08. Estimated completion is 2007-12.

What conditions does trial NCT00326339 study?

This clinical trial studies the following conditions: Rheumatoid Arthritis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00326339?

The interventions under investigation include: Placebo (DRUG), R788 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00326339?

This trial is sponsored by Rigel Pharmaceuticals, which has 68 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00326339 being conducted?

This trial has 20 study locations across California, Florida, Idaho, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial