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NCT00326339 · ClinicalTrials.gov registry record · Phase 2
Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)
A Phase 2 study of Rheumatoid Arthritis, sponsored by Rigel Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 189
- Enrollment target
- 20
- Study locations
NCT00326339: Completed Phase 2 study of Rheumatoid Arthritis, sponsored by Rigel Pharmaceuticals.
NCT00326339 is a Phase 2 study of Rheumatoid Arthritis that has completed, run by Rigel Pharmaceuticals. The registered enrollment target is 189 participants, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (96% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00326339, a Phase 2 study of Rheumatoid Arthritis, has completed, sponsored by Rigel Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 189 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, ascending dose, dose ranging study to evaluate up to three doses of R935788 (50 mg bid, 100 mg bid and 150 mg bid). Approximately 180 patients who have had rheumatoid arthritis for a minimum of 12 months and who have been receiving a weekly methotrexate (MTX) dose for a minimum of 6 months will be enrolled into the study.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG R788
Study Locations (20)
Florida
- DMI research - Ocala
- Renstar Medical Research - Ocala
- Arthritis & Osteoporosis Treatment Center - Orange Park
- Arthritis Associates Inc. - Orlando
- Arthritis Research of Florida, Inc. - Palm Harbor
- Arthritis Research of Florida - Palm Harbor
- Lovelace Scientific Resources - Sarasota
- The Center for Arthritis and Rheumatic Diseas - South Miami
Pennsylvania
- East Penn Rheumatology Associates - Bethlehem
- Altoona Ctr. for Clinical Research - Duncansville
California
- Pacific Arthritis Center Medical Group - Santa Maria
Idaho
- Coeur d'Alene Arthritis Clinical Trials - Coeur d'Alene
Illinois
- The Arthritis Center - Springfield
Indiana
- MMG Clinical Research - South Bend
Massachusetts
- Phase III Clinical Research - Fall River
Michigan
- Michigan Arthritis Research Center - Brighton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 189 participants |
| Start Date | 2006-08 |
| Est. Completion | 2007-12 |
| Phase | Phase 2 |
What the finished NCT00326339 record still lists
NCT00326339 is an interventional study that assigns participants to a tested intervention. The registered 189 participants enrollment target is mid-sized for trials with a published cap, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00326339 names 20 study sites across 12 states, led by Florida, Pennsylvania, California.
Frequently Asked Questions
What is clinical trial NCT00326339 about?
NCT00326339 is a clinical study titled "Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)". This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, ascending dose, dose ranging study to evaluate up to three doses of R935788 (50 mg bid, 100 mg bid and 150 mg bid). Approximately 180 patients who have had rheumatoid arthritis for a minimum of 12 months and who have been...
What is the current status of trial NCT00326339?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 189 participants. The study started on 2006-08. Estimated completion is 2007-12.
What conditions does trial NCT00326339 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis.
What interventions are being tested in trial NCT00326339?
The interventions under investigation include: Placebo (DRUG), R788 (DRUG).
Who is sponsoring clinical trial NCT00326339?
This trial is sponsored by Rigel Pharmaceuticals, which has 22 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00326339 being conducted?
This trial has 20 study locations across California, Florida, Idaho, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00326339's enrollment target sits among peer trials
189 89th of 197 higher than 109 of 197 other Rheumatoid Arthritis trials
participants (enrollment target), bucketed by value
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