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NCT00316940 · ClinicalTrials.gov registry record · Phase 1
Samarium 153 and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma
A Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, sponsored by Oncotherapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
- 4
- Study locations
NCT00316940: Completed Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, sponsored by Oncotherapeutics.
NCT00316940 is a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm that has completed, run by Oncotherapeutics. The registered enrollment target is 36 participants, below the 768-participant average among 26 other Multiple Myeloma and Plasma Cell Neoplasm trials with a reported enrollment target (95% lower). The trial reports 4 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00316940, a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, has completed, sponsored by Oncotherapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
- 4
- Study locations
Study Summary
RATIONALE: Radioactive substances, such as samarium 153, may release radiation as it breaks down and kill cancer cells. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Bortezomib may also make tumor cells more sensitive to radiation. Giving samarium 153 together with bortezomib may kill more cancer cells. PURPOSE: This phase I trial is studying the side effects and best dose of samarium 153 when given together with bortezomib in treating patients with relapsed or refractory multiple myeloma.
Conditions Studied
Interventions
- DRUG bortezomib
- RADIATION samarium Sm 153 lexidronam pentasodium
Study Locations (4)
California
- Comprehensive Blood and Cancer Center - Bakersfield
- Hematology-Oncology Medical Group of Fresno, Incorporated - Fresno
- - West Hollywood
Maryland
- Center for Cancer and Blood Disorders at Suburban Hospital - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2005-12 |
| Est. Completion | 2011-02 |
| Phase | Phase 1 |
What the finished NCT00316940 record still lists
NCT00316940 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 768-participant average among 26 other Multiple Myeloma and Plasma Cell Neoplasm trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Multiple Myeloma and Plasma Cell Neoplasm appearing as the primary indexed condition, and to 2 interventions - of which bortezomib is the first listed.
NCT00316940 reports a single indexed study location in California, Maryland.
Frequently Asked Questions
What is clinical trial NCT00316940 about?
NCT00316940 is a clinical study titled "Samarium 153 and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma". RATIONALE: Radioactive substances, such as samarium 153, may release radiation as it breaks down and kill cancer cells. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Bortezomib may also make tumor cells more sensitive to radiation. Giving sama...
What is the current status of trial NCT00316940?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2005-12. Estimated completion is 2011-02.
What conditions does trial NCT00316940 study?
This clinical trial studies the following conditions: Multiple Myeloma and Plasma Cell Neoplasm.
What interventions are being tested in trial NCT00316940?
The interventions under investigation include: bortezomib (DRUG), samarium Sm 153 lexidronam pentasodium (RADIATION).
Who is sponsoring clinical trial NCT00316940?
This trial is sponsored by Oncotherapeutics, which has 17 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00316940 being conducted?
This trial has 4 study locations across California, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00316940's enrollment target sits among peer trials
36 15th of 26 higher than 12 of 26 other Multiple Myeloma and Plasma Cell Neoplasm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma and Plasma Cell Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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