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NCT00006021 · ClinicalTrials.gov registry record · Phase 1

Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma

A Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, sponsored by University of Miami.

Completed
Registry status
Phase 1
Development phase
22
Enrollment target
4
Study locations

NCT00006021 is a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm that has completed, run by University of Miami. The registered enrollment target is 22 participants, below the 769-participant average among 26 other Multiple Myeloma and Plasma Cell Neoplasm trials with a reported enrollment target (97% lower). The trial reports 4 study locations across 1 state.

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The verdict

NCT00006021, a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, has completed, sponsored by University of Miami.

COMPLETED
Registry status
Phase 1
Development phase
22 participants
Enrollment target
4
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Vitamin C may increase the effectiveness of arsenic trioxide by making cancer cells more sensitive to the drug. PURPOSE: Phase I/II trial to determine the effectiveness of arsenic trioxide plus vitamin C in treating patients who have recurrent or refractory multiple myeloma.

Interventions

  • DRUG arsenic trioxide
  • DIETARY_SUPPLEMENT ascorbic acid

Study Locations (4)

Florida

  • Cedars Medical Center - Miami
  • University of Miami Sylvester Comprehensive Cancer Center - Miami
  • Baptist-South Miami Regional Cancer Program - Miami
  • Mount Sinai Comprehensive Cancer Center at Mount Sinai Medical Center - Miami Beach

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2000-06
Est. Completion 2007-03
Phase Phase 1

Sponsor

University of Miami

721 total trials

What the Registry Record Tells You About NCT00006021

The ClinicalTrials.gov registry entry for NCT00006021 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 769-participant average among 26 other Multiple Myeloma and Plasma Cell Neoplasm trials with a reported enrollment target (97% lower). The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma and Plasma Cell Neoplasm appearing as the primary indexed condition, and to 2 interventions - of which arsenic trioxide is the first listed.

NCT00006021 reports 4 study locations spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT00006021 about?

NCT00006021 is a clinical study titled "Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Vitamin C may increase the effectiveness of arsenic trioxide by making cancer cells more sensitive to the drug. PURPOSE: Phase I/II trial to determine the effectiveness of arseni...

What is the current status of trial NCT00006021?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2000-06. Estimated completion is 2007-03.

What conditions does trial NCT00006021 study?

This clinical trial studies the following conditions: Multiple Myeloma and Plasma Cell Neoplasm.

What interventions are being tested in trial NCT00006021?

The interventions under investigation include: arsenic trioxide (DRUG), ascorbic acid (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT00006021?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00006021 being conducted?

This trial has 4 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.