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NCT00258427 · ClinicalTrials.gov registry record · Phase 2

Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia

A Phase 2 study of Fanconi Anemia, sponsored by Masonic Cancer Center, University of Minnesota.

Completed
Registry status
Phase 2
Development phase
14
Enrollment target
1
Study location

NCT00258427 is a Phase 2 study of Fanconi Anemia that has completed, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 14 participants, below the 335-participant average among 15 other Fanconi Anemia trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00258427, a Phase 2 study of Fanconi Anemia, has completed, sponsored by Masonic Cancer Center, University of Minnesota.

COMPLETED
Registry status
Phase 2
Development phase
14 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: A bone marrow or umbilical cord blood transplant may be able to replace blood-forming cells that were destroyed by chemotherapy. Giving combination chemotherapy before a donor stem cell transplant may make the transplant more likely to work. This may be an effective treatment for patients with high risk Fanconi's anemia. PURPOSE: This clinical trial is studying how well combination chemotherapy works in treating high risk patients who are undergoing a donor stem cell transplant for Fanconi's anemia.

Conditions Studied

Interventions

  • DRUG cyclophosphamide
  • DRUG fludarabine phosphate
  • BIOLOGICAL filgrastim
  • DRUG busulfan
  • BIOLOGICAL anti-thymocyte globulin

Study Locations (1)

Minnesota

  • Masonic Cancer Center, University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2002-03-26
Est. Completion 2020-10-10
Phase Phase 2

What the Registry Record Tells You About NCT00258427

The ClinicalTrials.gov registry entry for NCT00258427 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 335-participant average among 15 other Fanconi Anemia trials with a reported enrollment target (96% lower). The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Fanconi Anemia appearing as the primary indexed condition, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00258427 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT00258427 about?

NCT00258427 is a clinical study titled "Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia". RATIONALE: A bone marrow or umbilical cord blood transplant may be able to replace blood-forming cells that were destroyed by chemotherapy. Giving combination chemotherapy before a donor stem cell transplant may make the transplant more likely to work. This may be an effective treatment for patients...

What is the current status of trial NCT00258427?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2002-03-26. Estimated completion is 2020-10-10.

What conditions does trial NCT00258427 study?

This clinical trial studies the following conditions: Fanconi Anemia.

What interventions are being tested in trial NCT00258427?

The interventions under investigation include: cyclophosphamide (DRUG), fludarabine phosphate (DRUG), filgrastim (BIOLOGICAL), busulfan (DRUG), anti-thymocyte globulin (BIOLOGICAL).

Who is sponsoring clinical trial NCT00258427?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00258427 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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