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NCT00114114 · ClinicalTrials.gov registry record · NA

Dose-Response of Gonadal Steroids and Bone Turnover in Older Men

A NA study of Healthy Volunteers, sponsored by Massachusetts General Hospital.

Completed
Registry status
NA
Development phase
177
Enrollment target
1
Study location

NCT00114114: Completed NA study of Healthy Volunteers, sponsored by Massachusetts General Hospital.

NCT00114114 is a NA study of Healthy Volunteers that has completed, run by Massachusetts General Hospital. The registered enrollment target is 177 participants, below the 481-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00114114, a NA study of Healthy Volunteers, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
NA
Development phase
177 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine the levels of testosterone and/or estradiol at which changes in bone turnover, body composition, strength, sexual function etc. begin to occur in older men. This information may help determine when to intervene with hormone replacement therapy in aging men.

Conditions Studied

Interventions

  • DRUG Testosterone
  • DRUG Goserelin acetate

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 177 participants
Start Date 2004-09
Est. Completion 2017-11-01
Phase NA
Massachusetts General Hospital

2,032 total trials

What the finished NCT00114114 record still lists

NCT00114114 is an interventional study that assigns participants to a tested intervention. The registered 177 participants enrollment target is mid-sized for trials with a published cap, below the 481-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (63% lower).

The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 2 interventions - of which Testosterone is the first listed.

NCT00114114 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00114114 about?

NCT00114114 is a clinical study titled "Dose-Response of Gonadal Steroids and Bone Turnover in Older Men". The purpose of this study is to determine the levels of testosterone and/or estradiol at which changes in bone turnover, body composition, strength, sexual function etc. begin to occur in older men. This information may help determine when to intervene with hormone replacement therapy in aging men.

What is the current status of trial NCT00114114?

This trial is currently completed. It is a NA study. The enrollment target is 177 participants. The study started on 2004-09. Estimated completion is 2017-11-01.

What conditions does trial NCT00114114 study?

This clinical trial studies the following conditions: Healthy Volunteers.

What interventions are being tested in trial NCT00114114?

The interventions under investigation include: Testosterone (DRUG), Goserelin acetate (DRUG).

Who is sponsoring clinical trial NCT00114114?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00114114 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteers

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00114114's enrollment target sits among peer trials

177 54th of 283 higher than 230 of 283 other Healthy Volunteers trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00114114, the US trial registry maintained by the National Library of Medicine. NCT00114114 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.