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NCT00006244 · ClinicalTrials.gov registry record · Phase 2

Melphalan, Peripheral Stem Cell Transplantation, and Interleukin-2 Followed by Interferon Alfa in Treating Patients With Advanced Multiple Myeloma

A Phase 2 study of Refractory Multiple Myeloma and Stage III Multiple Myeloma, sponsored by Fred Hutchinson Cancer Center.

Completed
Registry status
Phase 2
Development phase
36
Enrollment target
1
Study location

NCT00006244 is a Phase 2 study of Refractory Multiple Myeloma and Stage III Multiple Myeloma that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 36 participants, below the 48-participant average among 67 other Refractory Multiple Myeloma trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00006244, a Phase 2 study of Refractory Multiple Myeloma and Stage III Multiple Myeloma, has completed, sponsored by Fred Hutchinson Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

This phase II trial studies the effectiveness of melphalan, peripheral stem cell transplantation, and interleukin-2 followed by interferon alfa in treating patients who have advanced multiple myeloma (MM). Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. Interleukin-2 (IL2) may stimulate a person's white blood cells to kill multiple myeloma cells. Interferon alfa may interfere with the growth of cancer cells

Interventions

  • DRUG melphalan
  • BIOLOGICAL aldesleukin
  • BIOLOGICAL recombinant interferon alfa
  • PROCEDURE in vitro-treated peripheral blood stem cell transplantation

Study Locations (1)

Washington

  • Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium - Seattle

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2000-02
Est. Completion 2016-04
Phase Phase 2

Sponsor

Fred Hutchinson Cancer Center

483 total trials

What the Registry Record Tells You About NCT00006244

The ClinicalTrials.gov registry entry for NCT00006244 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 48-participant average among 67 other Refractory Multiple Myeloma trials with a reported enrollment target (25% lower). The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Refractory Multiple Myeloma appearing as the primary indexed condition, and to 4 interventions - of which melphalan is the first listed.

NCT00006244 reports 1 study location spanning 1 distinct geographic area - top geographies include Washington.

Frequently Asked Questions

What is clinical trial NCT00006244 about?

NCT00006244 is a clinical study titled "Melphalan, Peripheral Stem Cell Transplantation, and Interleukin-2 Followed by Interferon Alfa in Treating Patients With Advanced Multiple Myeloma". This phase II trial studies the effectiveness of melphalan, peripheral stem cell transplantation, and interleukin-2 followed by interferon alfa in treating patients who have advanced multiple myeloma (MM). Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop g...

What is the current status of trial NCT00006244?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2000-02. Estimated completion is 2016-04.

What conditions does trial NCT00006244 study?

This clinical trial studies the following conditions: Refractory Multiple Myeloma, Stage III Multiple Myeloma, Stage II Multiple Myeloma, Stage I Multiple Myeloma.

What interventions are being tested in trial NCT00006244?

The interventions under investigation include: melphalan (DRUG), aldesleukin (BIOLOGICAL), recombinant interferon alfa (BIOLOGICAL), in vitro-treated peripheral blood stem cell transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00006244?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00006244 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.