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NCT00002753 · ClinicalTrials.gov registry record · Phase 1
Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas
A Phase 1 study of Brain and Central Nervous System Tumors, sponsored by Duke University.
- Completed
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
- 1
- Study location
NCT00002753: Completed Phase 1 study of Brain and Central Nervous System Tumors, sponsored by Duke University.
NCT00002753 is a Phase 1 study of Brain and Central Nervous System Tumors that has completed, run by Duke University. The registered enrollment target is 6 participants, below the 183-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00002753, a Phase 1 study of Brain and Central Nervous System Tumors, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
- 1
- Study location
Study Summary
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: Phase I trial to determine the effectiveness of monoclonal antibody in treating patients with recurrent gliomas.
Conditions Studied
Interventions
- RADIATION iodine I 131 monoclonal antibody 81C6
Study Locations (1)
North Carolina
- Duke Comprehensive Cancer Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 1991-11 |
| Est. Completion | 2001-04 |
| Phase | Phase 1 |
What the finished NCT00002753 record still lists
NCT00002753 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 183-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 1 intervention - of which iodine I 131 monoclonal antibody 81C6 is the first listed.
NCT00002753 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT00002753 about?
NCT00002753 is a clinical study titled "Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas". RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: Phase I trial to determine the effectiveness of monoclonal antibody in treating patients with recurrent gliomas.
What is the current status of trial NCT00002753?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 1991-11. Estimated completion is 2001-04.
What conditions does trial NCT00002753 study?
This clinical trial studies the following conditions: Brain and Central Nervous System Tumors.
What interventions are being tested in trial NCT00002753?
The interventions under investigation include: iodine I 131 monoclonal antibody 81C6 (RADIATION).
Who is sponsoring clinical trial NCT00002753?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00002753 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain and Central Nervous System Tumors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00002753's enrollment target sits among peer trials
6 44th of 45 higher than 1 of 45 other Brain and Central Nervous System Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain and Central Nervous System Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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