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Mafosfamide in Treating Patients With Progressive or Refractory Meningeal Tumors
NCT00031928 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to determine the effectiveness of mafosfamide in treating patients who have progressive or refractory meningeal tumors.
Conditions Studied
Interventions
- DRUG mafosfamide
Study Locations (9)
Texas
- Texas Children's Cancer Center — Houston
- University of Texas - MD Anderson Cancer Center — Houston
California
- Children's Hospital Los Angeles — Los Angeles
District of Columbia
- Children's National Medical Center — Washington D.C.
Maryland
- Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support — Bethesda
Michigan
- Josephine Ford Cancer Center at Henry Ford Hospital — Detroit
Minnesota
- Mayo Clinic Cancer Center — Rochester
Vermont
- Neurological Research Center, Inc. — Bennington
Washington
- Children's Hospital and Regional Medical Center - Seattle — Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,000 participants |
| Start Date | 2002-01 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00031928
The ClinicalTrials.gov registry entry for NCT00031928 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 2,390 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 1 intervention — of which mafosfamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00031928 reports 9 study locations spanning 8 distinct geographic areas — top geographies include Texas, California, District of Columbia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00031928 about?
NCT00031928 is a clinical study titled "Mafosfamide in Treating Patients With Progressive or Refractory Meningeal Tumors". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to determine the effectiveness of mafosfamide in treating patients who have progressive or refractory meningeal tumors.
What is the current status of trial NCT00031928?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 3,000 participants. The study started on 2002-01.
What conditions does trial NCT00031928 study?
This clinical trial studies the following conditions: Brain and Central Nervous System Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00031928?
The interventions under investigation include: mafosfamide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00031928?
This trial is sponsored by National Cancer Institute (NCI), which has 2,390 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00031928 being conducted?
This trial has 9 study locations across California, District of Columbia, Maryland, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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