United Therapeutics

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, United Therapeutics sits in the top decile of US sponsors by registered trial count (#328 of 15,742 sponsors by registered trial count).

63 total trials 5 currently recruiting 39 completed top decile by trial count

United Therapeutics: 63 sponsored US clinical trials, 5 recruiting.

United Therapeutics sponsors 63 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 39 completed. 26 of these trials are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pulmonary Arterial Hypertension, with 4 trials.

Top-decile sponsor footprint

United Therapeutics ranks in the top decile of sponsors by registered trial count (#328 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 13/100

39 of 56 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (69.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

63 total, page 2 of 2

COMPLETED Phase 4

Safety Evaluation of Inhaled Treprostinil Administration Following Transition From Inhaled Ventavis in Pulmonary Arterial Hypertension (PAH) Subjects

NCT00741819

TERMINATED Phase 4

Rapid Switch From Flolan to Remodulin in the Outpatient Clinic

NCT00643604

TERMINATED Phase 4

Transitioning To IV Remodulin From Ventavis in Patients With PAH: Safety, Efficacy and Treatment Satisfaction

NCT00458042

TERMINATED Phase 4

Safety, Efficacy, and Treatment Satisfaction Switching From Flolan to Remodulin Using the Crono Five Ambulatory Pump in Patients With PAH

NCT00439946

COMPLETED Phase 3

An Open-Label Extension Trial of UT-15C Sustained-release (SR) in Subjects With Pulmonary Arterial Hypertension

NCT01027949

COMPLETED Phase 3

FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

NCT00325403

COMPLETED Phase 3

FREEDOM-C: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor for the Treatment of Pulmonary Arterial Hypertension (PAH)

NCT00325442

COMPLETED Phase 4

Safety, Efficacy and Treatment Satisfaction in Patients With PAH Rapidly Switched From Epoprostenol to Remodulin

NCT00373360

COMPLETED Phase 3

Clinical Investigation Into Inhaled Treprostinil Sodium in Patients With Severe Pulmonary Arterial Hypertension (PAH)

NCT00147199

TERMINATED Phase 2

Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft

NCT00067041

TERMINATED Phase 3

Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures

NCT00060996

COMPLETED Phase 4

A Transition Study From Flolan® to Remodulin® in Patients With Pulmonary Arterial Hypertension

NCT00058929

COMPLETED Phase 3

Phase III Randomized Study of UT-15 in Patients With Primary Pulmonary Hypertension

NCT00004497

← Previous Page 2 of 2

What is open in the United Therapeutics pipeline

5 recruiting of 63 indexed (8% open); 39 completed (62%).

Phase mix: 26 late (III/IV) vs 28 early (I/II) (balanced across stages).

Top condition: Pulmonary Arterial Hypertension (4 trials), 8 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

United Therapeutics: open-pipeline peers nationwide

Peers matched on 63 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

United Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15%20% Total trials Recruiting share United TherapeuticsActelionHennepin Healthcare Research InstituteUniversity of OregonCephalonNovo Nordisk A/SArcutis BiotherapeuticsMedtronic EndovascularNovartis Pharmaceuticals
United Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

United Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 63 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this United Therapeutics page

63 registered trials is a research-attention snapshot, not an endorsement of United Therapeutics or any single study.

  • 5 of United Therapeutics's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Pulmonary Arterial Hypertension is the condition United Therapeutics studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pulmonary Arterial Hypertension trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

United Therapeutics pipeline card: 63 registered trials from official public datasets.Report a data error.