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A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease
NCT07214571 · View on ClinicalTrials.gov ↗
Study Summary
The main purpose of this study is to investigate the antiviral effect of S-337395 compared with placebo among nonhospitalized adult participants with high-risk factors for progression to severe RSV infection starting intervention within 72 hours of RSV symptom onset.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG S-337395
Study Locations (20)
Florida
- Hope Clinical Trials - 3970 W Flagler St. — Coral Gables
- Beautiful Minds Clinical Research Center — Cutler Bay
- Doral Medical Research — Hialeah
- Southern Clinical Research — Miami
- LCC Medical Research - Miami - BTC - PPDS — Miami
- Nuren Medical and Research Center — Miami
- Continental Clinical Research, LLC — Miami
- Dynamic Medical Research, LLC - Miami — Miami
- Miami Clinical Research, LLP. — Miami
- Reed Medical Research — Miami
- Palm Springs Community Health Center — Miami Lakes
- Oceanic Research Group, LLC — North Miami Beach
- CDC Research Institute, LLC — Port Saint Lucie
- Cordova Research Insittute — Sweetwater
- Better Life Clinical Research LLC — Tampa
- Research Bay,Inc. — Tampa
- Santos Research Center - 5927 Webb Rd — Tampa
California
- LA Universal Research Center, Inc. — Los Angeles
- Med Partnes, Inc - Elligo- PPDS — Toluca Lake
Georgia
- Covenant Pulmonary Criticial Care and Research Ins — East Point
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2025-12-11 |
| Est. Completion | 2026-12-30 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07214571
The ClinicalTrials.gov registry entry for NCT07214571 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 192 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shionogi, which has 52 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Respiratory Syncytial Virus Infections appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07214571 reports 20 study locations spanning 3 distinct geographic areas — top geographies include Florida, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07214571 about?
NCT07214571 is a clinical study titled "A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease". The main purpose of this study is to investigate the antiviral effect of S-337395 compared with placebo among nonhospitalized adult participants with high-risk factors for progression to severe RSV infection starting intervention within 72 hours of RSV symptom onset.
What is the current status of trial NCT07214571?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 192 participants. The study started on 2025-12-11. Estimated completion is 2026-12-30.
What conditions does trial NCT07214571 study?
This clinical trial studies the following conditions: Respiratory Syncytial Virus Infections. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07214571?
The interventions under investigation include: Placebo (DRUG), S-337395 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07214571?
This trial is sponsored by Shionogi, which has 52 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07214571 being conducted?
This trial has 20 study locations across California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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