Praxis Precision Medicines

13 total trials 6 currently recruiting 5 completed

Praxis Precision Medicines sponsors 13 registered US clinical trials on ClinicalTrials.gov, 6 of them currently recruiting, and 5 completed. 3 of these trials are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is SCN2A Encephalopathy, with 2 trials.

Trial Pipeline

13 total, page 1 of 1

RECRUITING Phase 3

Double-blind, Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures

NCT07505004

RECRUITING Phase 3

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

NCT07019922

RECRUITING Phase 3

A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine

NCT07010471

RECRUITING Phase 2

An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures

NCT06908356

RECRUITING Phase 2

Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)

NCT06999902

RECRUITING Phase 1

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

NCT05737784

ACTIVE NOT RECRUITING Phase 2

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

NCT05818553

COMPLETED

A Prospective, Remote Observational Study in Pediatric Participants With Early-Onset SCN2A-Developmental and Epileptic Encephalopathy

NCT05407727

TERMINATED Phase 2

A Clinical Trial of PRAX-114 in Participants With Post-Traumatic Stress Disorder

NCT05260541

COMPLETED Phase 2

A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor

NCT05021991

COMPLETED Phase 2

A Clinical Trial of Adjunctive and Monotherapy PRAX-114 in Participants With Major Depressive Disorder

NCT04969510

COMPLETED Phase 2

A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder

NCT04832425

COMPLETED Phase 2

A Clinical Trial of PRAX-944 in Participants With Essential Tremor

NCT05021978

What the Pipeline for Praxis Precision Medicines Shows

According to the ClinicalTrials.gov registry, Praxis Precision Medicines is linked to 13 US clinical trials across every stage of research activity. Of those, 6 studies are currently recruiting, about 46% of the sponsor's indexed portfolio, and 5 are already marked complete, representing roughly 38% of the total.

The phase mix for Praxis Precision Medicines reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 9 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Praxis Precision Medicines is SCN2A Encephalopathy with 2 linked trials, and 8 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.