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NCT04832425 · ClinicalTrials.gov registry record · Phase 2

A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder

A Phase 2 study, sponsored by Praxis Precision Medicines.

Completed
Registry status
Phase 2
Development phase
216
Enrollment target

NCT04832425 is a Phase 2 study that has completed, run by Praxis Precision Medicines. The registered enrollment target is 216 participants.

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The verdict

NCT04832425, a Phase 2 study, has completed, sponsored by Praxis Precision Medicines.

COMPLETED
Registry status
Phase 2
Development phase
216 participants
Enrollment target

Study Summary

This is a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of PRAX-114 in participants with moderate to severe major depressive disorder (MDD). Participants will be randomized to receive 28 days of either 40 mg PRAX-114 or placebo in a 1:1 ratio.

Interventions

  • DRUG Placebo
  • DRUG PRAX-114

Trial Details

FieldValue
Enrollment Target 216 participants
Start Date 2021-03-30
Est. Completion 2022-05-05
Phase Phase 2

Sponsor

Praxis Precision Medicines

13 total trials

What the Registry Record Tells You About NCT04832425

The ClinicalTrials.gov registry entry for NCT04832425 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 216 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Praxis Precision Medicines, which has 13 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04832425 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04832425 about?

NCT04832425 is a clinical study titled "A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder". This is a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of PRAX-114 in participants with moderate to severe major depressive disorder (MDD). Participants will be randomized to receive 28 days of either 40 mg PRAX-114 or placebo in a 1:1 ratio.

What is the current status of trial NCT04832425?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 216 participants. The study started on 2021-03-30. Estimated completion is 2022-05-05.

What interventions are being tested in trial NCT04832425?

The interventions under investigation include: Placebo (DRUG), PRAX-114 (DRUG).

Who is sponsoring clinical trial NCT04832425?

This trial is sponsored by Praxis Precision Medicines, which has 13 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.