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NCT06999902 · ClinicalTrials.gov registry record · Phase 2

Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)

A Phase 2 study of Focal Seizure, sponsored by Praxis Precision Medicines.

Recruiting
Registry status
Phase 2
Development phase
230
Enrollment target
20
Study locations

NCT06999902 is a Phase 2 study of Focal Seizure that is actively recruiting participants, run by Praxis Precision Medicines. The registered enrollment target is 230 participants. The trial reports 20 study locations across 12 states.

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The verdict

NCT06999902, a Phase 2 study of Focal Seizure, is actively recruiting participants, sponsored by Praxis Precision Medicines.

RECRUITING
Registry status
Phase 2
Development phase
230 participants
Enrollment target
20
Study locations

Study Summary

A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults With Focal Seizures (POWER1)

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG 20mg/day PRAX-628 for 6 weeks then 30mg/day PRAX-628 for remaining 6 weeks

Study Locations (20)

Texas

  • Praxis Research Site - El Paso
  • Praxis Research Site - Frisco
  • Praxis Research Site - Round Rock
  • Praxis Research Site - Seabrook

Other

  • Praxis Research Site - Barcelona
  • Praxis Research Site - Barcelona
  • Praxis Research Site - Barcelona
  • Praxis Research Site - Granda

Florida

  • Praxis Research Site - DeLand
  • Praxis Research Site - Miami Lakes

Missouri

  • Praxis Research Site - Chesterfield
  • Praxis Research Site - Ozark

Arizona

  • Praxis Research Site - Phoenix

Illinois

  • Praxis Research Site - Chicago

Louisiana

  • Praxis Research Site - Lafayette

Maryland

  • Praxis Research Site - Bethesda

Trial Details

FieldValue
Enrollment Target 230 participants
Start Date 2024-12-11
Est. Completion 2025-12-08
Phase Phase 2

Sponsor

Praxis Precision Medicines

13 total trials

What the Registry Record Tells You About NCT06999902

The ClinicalTrials.gov registry entry for NCT06999902 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 230 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Praxis Precision Medicines, which has 13 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Focal Seizure appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06999902 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Texas, Other, Florida.

Frequently Asked Questions

What is clinical trial NCT06999902 about?

NCT06999902 is a clinical study titled "Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)". A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults With Focal Seizures (POWER1)

What is the current status of trial NCT06999902?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 230 participants. The study started on 2024-12-11. Estimated completion is 2025-12-08.

What conditions does trial NCT06999902 study?

This clinical trial studies the following conditions: Focal Seizure.

What interventions are being tested in trial NCT06999902?

The interventions under investigation include: Placebo (DRUG), 20mg/day PRAX-628 for 6 weeks then 30mg/day PRAX-628 for remaining 6 weeks (DRUG).

Who is sponsoring clinical trial NCT06999902?

This trial is sponsored by Praxis Precision Medicines, which has 13 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06999902 being conducted?

This trial has 20 study locations across Arizona, Florida, Illinois, Louisiana, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.