Millennium Pharmaceuticals

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Millennium Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#207 of 15,742 sponsors by registered trial count).

135 total trials none currently recruiting 119 completed early-phase tilt top decile by trial count

Millennium Pharmaceuticals: 135 sponsored US clinical trials, none currently recruiting.

Millennium Pharmaceuticals sponsors 135 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 119 completed. 17 of these trials are in Phase 3-4 (later-stage) and 117 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Lymphoma, with 3 trials.

Top-decile sponsor footprint

Millennium Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#207 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

119 of 135 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

135 total, page 3 of 3

COMPLETED Phase 3

Study of Vedolizumab (MLN0002) in Patients With Moderate to Severe Ulcerative Colitis

NCT00783718

COMPLETED Phase 1

Safety Study of TAK-593 Given Orally in Subjects With Nonhematologic Advanced Cancer

NCT00773929

COMPLETED Phase 3

Study of Vedolizumab (MLN0002) in Patients With Moderate to Severe Crohn's Disease

NCT00783692

COMPLETED Phase 2

Phase 2 Study of VELCADE (Bortezomib) in Patients With Relapsed Follicular Lymphoma

NCT00715208

COMPLETED Phase 1

Study of MLN8237 in Participants With Advanced Hematological Malignancies

NCT00697346

COMPLETED Phase 1

Study of MLN4924, a Novel Inhibitor of Nedd8 Activating Enzyme, in Adult Patients With Lymphoma or Multiple Myeloma

NCT00722488

COMPLETED Phase 3

Study of the Combination of Rituximab, Cyclophosphamide, Doxorubicin, VELCADE, and Prednisone or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Mantle Cell Lymphoma

NCT00722137

COMPLETED Phase 1

Study of MLN4924 in Adult Patients With Nonhematologic Malignancies

NCT00677170

COMPLETED Phase 1

Safety Study of TAK-700 in Subjects With Prostate Cancer.

NCT00569153

COMPLETED Phase 2

A Phase II Study of VELCADE (Bortezomib) in Combination With Bendamustine and Rituximab in Subjects With Relapsed or Refractory Follicular Lymphoma

NCT00636792

COMPLETED

Mifamurtide (L-MTP-PE) for High-Risk Osteosarcoma

NCT00631631

COMPLETED Phase 1

Phase 1/2 Study of VELCADE® in Combination With Other Drugs to Treat Previously Untreated Multiple Myeloma Patients

NCT00507442

COMPLETED Phase 1

A Safety and Pharmacokinetic Study of TAK-285 in Patients With Advanced Cancer

NCT00535522

COMPLETED Phase 3

Velcade,Thalidomide, and Dexamethasone Versus Velcade and Dexamethasone Versus Velcade, Melphalan, and Prednisone

NCT00507416

COMPLETED Phase 1

A Study of MLN8237, a Novel Aurora A Kinase Inhibitor, in Participants With Advanced Solid Tumors

NCT00500903

COMPLETED Phase 3

Study of VELCADE and Rituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

NCT00312845

TERMINATED Phase 1

A Study of MLN8054 in Patients With Advanced Solid Tumors

NCT00249301

TERMINATED Phase 2

A Study of Tarceva for Use in Patients With Relapsed or Refractory Metastatic Non-Small Cell Lung Cancer

NCT00283634

COMPLETED Phase 1

Open-Label Phase 1/2 Study of VELCADE for Injection in Patients With Light-chain (AL)-Amyloidosis

NCT00298766

TERMINATED Phase 2

VELCADE in Previously Treated Patients With Stage IIIB and IV Bronchioloalveolar Carcinoma (BAC) and Adenocarcinoma With BAC Features

NCT00117351

COMPLETED Phase 1

MLN518 in Combination With Standard Induction Chemo. for Treatment of Patients With Newly Diagnosed Acute Myelogenous Leukemia

NCT00274248

COMPLETED Phase 3

VELCADE/Melphalan/Prednisone Versus Melphalan/Prednisone in Patients With Previously Untreated Multiple Myeloma

NCT00111319

COMPLETED Phase 2

VELCADE® (Bortezomib) With Rituximab in Subjects With Relapsed or Refractory Indolent B-Cell Lymphoma

NCT00085696

COMPLETED Phase 1

MLN2704 in Subjects With Metastatic Androgen-Independent Prostate Cancer

NCT00070837

COMPLETED Phase 2

VELCADE in Subjects With Relapsed or Refractory Mantle Cell Lymphoma

NCT00063713

COMPLETED Phase 2

Phase 2 Study of VELCADE Alone or VELCADE® Plus Docetaxel in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

NCT00051974

COMPLETED Phase 2

Phase 2b Study of VELCADE Alone and VELCADE Plus Irinotecan in Patients With Relapsed or Refractory Colorectal Carcinoma

NCT00051987

COMPLETED Phase 1

Phase I/II Dose Escalation Study of VELCADE® and Docetaxel in Patients With Advanced Androgen-Independent Prostate Cancer

NCT00064610

COMPLETED Phase 1

A Trial of MLN2704 in Subjects With Metastatic Androgen Independent Prostate Cancer

NCT00052000

COMPLETED Phase 3

PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

NCT00048230

COMPLETED Phase 1

Safety and Tolerance Study of Oral Doses of CT53518 to Treat Patients With Acute Myelogenous Leukemia (AML)

NCT00064584

COMPLETED Phase 3

A Study of PS-341 Given to Patients With Multiple Myeloma Who Experienced Progressive Disease After Receiving Dexamethasone in M34101-039

NCT00063726

COMPLETED Phase 4

Evaluation of VELCADE Given as Retreatment to Multiple Myeloma Patients for Efficacy, Safety and Tolerability

NCT00257114

COMPLETED Phase 1

Ketoconazole Administration: How it is Affected by the Body and Broken Down and How it Acts on the Body When Used With Velcade

NCT00129207

COMPLETED Phase 1

Open-Label Study to Assess the Effect of Omeprazole on the Pharmacokinetics of VELCADE in Patients With Either Advanced Solid Tumors or Non-Hodgkin's Lymphoma.

NCT00298779

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How the Millennium Pharmaceuticals early-phase archive is shaped

135 indexed studies, none listed as recruiting (0% open); 119 completed (88%).

Phase mix: 17 late (III/IV) vs 117 early (I/II) (early-phase heavy).

Top condition: Lymphoma (3 trials), 9 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Millennium Pharmaceuticals: archived-pipeline peers nationwide

Peers matched on 135 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Millennium Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 0%10%20%30% Total trials Recruiting share Millennium PharmaceuticalsThe Miriam HospitalGeorge Washington UniversityShirley Ryan AbilityLabSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University10xBio22nd Century Group23andMe3-C Institute for Social Development
Millennium Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Millennium Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 135 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Millennium Pharmaceuticals page

135 registered trials is a research-attention snapshot, not an endorsement of Millennium Pharmaceuticals or any single study.

  • None of Millennium Pharmaceuticals's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Lymphoma is the condition Millennium Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Lymphoma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Millennium Pharmaceuticals pipeline card: 135 registered trials from official public datasets.Report a data error.