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COMPLETED Phase 1

Study of MLN4924 in Adult Patients With Nonhematologic Malignancies

NCT00677170 · View on ClinicalTrials.gov ↗

Study Summary

This study is an open-label, multicenter, Phase 1, dose escalation study of MLN4924 in adult patients with nonhematologic malignancies. This study will be the first to administer MLN4924 in humans. The patient population will consist of adults with any form of nonhematologic malignancy for which standard, curative, life prolonging, or palliative treatment does not exist or is no longer effective.

Interventions

  • DRUG MLN4924

Study Locations (3)

Texas

  • Cancer Therapy & Research Center at the UT Health Science Center — San Antonio
  • Institute for Drug Development — San Antonio

Georgia

  • Emory University Hospital — Atlanta

Trial Details

FieldValue
Enrollment Target 62 participants
Start Date 2008-04
Est. Completion 2012-12
Phase Phase 1

Sponsor

Millennium Pharmaceuticals

21 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00677170

The ClinicalTrials.gov registry entry for NCT00677170 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 62 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Millennium Pharmaceuticals, which has 21 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Nonhematologic Malignancies appearing as the primary indexed condition, and to 1 intervention — of which MLN4924 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00677170 reports 3 study locations spanning 2 distinct geographic areas — top geographies include Texas, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00677170 about?

NCT00677170 is a clinical study titled "Study of MLN4924 in Adult Patients With Nonhematologic Malignancies". This study is an open-label, multicenter, Phase 1, dose escalation study of MLN4924 in adult patients with nonhematologic malignancies. This study will be the first to administer MLN4924 in humans. The patient population will consist of adults with any form of nonhematologic malignancy for which sta...

What is the current status of trial NCT00677170?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 62 participants. The study started on 2008-04. Estimated completion is 2012-12.

What conditions does trial NCT00677170 study?

This clinical trial studies the following conditions: Advanced Nonhematologic Malignancies. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00677170?

The interventions under investigation include: MLN4924 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00677170?

This trial is sponsored by Millennium Pharmaceuticals, which has 21 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00677170 being conducted?

This trial has 3 study locations across Georgia, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial