M.D. Anderson Cancer Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, M.D. Anderson Cancer Center sits in the top decile of US sponsors by registered trial count (#3 of 15,751 sponsors by registered trial count).

2,692 total trials 549 currently recruiting 1201 completed early-phase tilt top decile by trial count

M.D. Anderson Cancer Center: 2,692 sponsored US clinical trials, 549 recruiting.

M.D. Anderson Cancer Center sponsors 2,692 registered US clinical trials on ClinicalTrials.gov, 549 of them currently recruiting, and 1,201 completed. 124 of these trials are in Phase 3-4 (later-stage) and 1,719 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hematopoietic and Lymphoid Cell Neoplasm, with 44 trials.

Top-decile sponsor footprint

M.D. Anderson Cancer Center ranks in the top decile of sponsors by registered trial count (#3 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,692 total, page 31 of 54

COMPLETED NA

Changes in Patient Reported Constipation Among Advanced Cancer Patients After Receiving an Educational Intervention

NCT02422329

COMPLETED Early Phase 1

Ultraviolet (UV) Photography in Adolescents

NCT02426853

TERMINATED Phase 2

Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

NCT02399917

TERMINATED Phase 1

Trial of PCI-32765 (BTK Inhibitor) in Combination With Carfilzomib in Relapse/Refractory Mantle Cell Lymphoma

NCT02269085

COMPLETED Phase 2

Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancer

NCT02282345

COMPLETED Phase 1

Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CML

NCT02311998

COMPLETED Phase 1

Ganetespib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-III Esophageal Cancer

NCT02389751

COMPLETED Phase 2

Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia

NCT02397720

COMPLETED Phase 1

Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung Cancer

NCT02225405

COMPLETED Phase 2

Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers

NCT02392637

COMPLETED Phase 1

A Phase I/II Study of Ibrutinib in Previously Treated Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer

NCT02321540

TERMINATED Phase 2

Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission

NCT02302846

COMPLETED Phase 1

Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors

NCT02271711

TERMINATED Phase 1

An Open-Label, Phase I/II Study of Nilotinib (Tasigna) and MEK-162 (ARRY-162) Used in Combination for Patients With Refractory or Advanced Chronic Myeloid Leukemia and Philadelphia Positive Acute Leukemia (Protocol CAMN107AUS41T)

NCT02225574

COMPLETED NA

Cordotomy for Refractory Cancer Pain

NCT02345629

COMPLETED Phase 1

Cord Blood Natural Killer (NK) Cells in Leukemia/Lymphoma

NCT02280525

COMPLETED Phase 2

Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Cytomegalovirus (CMV) Reactivation

NCT02210065

COMPLETED NA

PCORI-CER-1306-03385 Informed Decisions About Lung Cancer Screening

NCT02286713

TERMINATED Phase 2

Metformin in Non Small Cell Lung Cancer (NSCLC)

NCT02285855

COMPLETED Phase 2

Cabozantinib S-malate in Treating Patients With Metastatic Pheochromocytomas or Paragangliomas That Cannot Be Removed by Surgery

NCT02302833

COMPLETED Phase 1

Ruxolitinib Phosphate and Decitabine in Treating Patients With Relapsed or Refractory or Post Myeloproliferative Acute Myeloid Leukemia

NCT02257138

COMPLETED Phase 2

Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer

NCT02366130

TERMINATED Phase 2

Denosumab for Breast Cancer With Bone Mets

NCT01952054

COMPLETED Phase 2

Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD Mutation

NCT02196857

COMPLETED Early Phase 1

Preoperative Rehabilitation During Neoadjuvant Therapy for Pancreatic Cancer

NCT02295956

COMPLETED

Interventional Validation of an MDS-Specific Measure of Quality of Life: Assessing the Responsiveness of the Quality of Life in Myelodysplasia Scale (QUALMS-1) to Different Hypomethylating Agent Regimens for Low and Intermediate Risk Disease

NCT02378701

COMPLETED Phase 1

Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma

NCT01740557

COMPLETED NA

Mindfulness Based Couples Therapy

NCT02349217

COMPLETED Phase 2

CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Melanoma

NCT02027935

COMPLETED Phase 2

Dose Adjusted EPOCH Regimen in Combination With Ofatumumab or Rituximab in Treating Patients With Newly Diagnosed or Relapsed or Refractory Burkitt Lymphoma or Relapsed or Refractory Acute Lymphoblastic Leukemia

NCT02199184

COMPLETED Phase 2

Ruxolitinib and Pracinostat Combination Therapy for Patients With Myelofibrosis (MF)

NCT02267278

COMPLETED NA

A Culturally Sensitive Social Support Intervention

NCT02946697

TERMINATED NA

Mobile Media-Rich Interactive Guideline System (MMRIGS) Pilot Study

NCT02302859

COMPLETED Phase 2

LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis

NCT02098161

TERMINATED Phase 2

Lenalidomide as Immune Adjuvant in Patient's With Chronic Lymphocytic Leukemia (CLL)

NCT01924169

COMPLETED NA

ICU Triage Practices in a Cancer Hospital

NCT03401411

COMPLETED Phase 2

Lenalidomide in Treating Patients With High Risk Acute Myeloid Leukemia in Remission

NCT02126553

COMPLETED Phase 2

Guadecitabine in Treating Patients With Higher-Risk Myelodysplastic Syndromes

NCT02131597

COMPLETED NA

Neurological Effects of Acupuncture to Prevent Radiation-induced Xerostomia

NCT02292368

COMPLETED Phase 1

LDE225 + Everolimus in Advanced Gastroesophageal Adenocarcinoma

NCT02138929

COMPLETED

Rational Therapeutics Based on Matched Tumor and Normal Tissue

NCT02272595

COMPLETED NA

Exploring the Neuro-Immune Basis of Cancer-Related Fatigue Using Behavioral Measures

NCT02255773

COMPLETED Phase 2

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

NCT02135874

TERMINATED NA

Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer

NCT02140021

COMPLETED Phase 2

Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)

NCT02269280

COMPLETED Phase 4

Accuracy of an Echo-Stress Protocol Using Regadenoson With Speckle Tracking

NCT02130453

COMPLETED NA

Yoga Program for Lung Cancer Patients and Caregivers

NCT02196844

TERMINATED Phase 2

Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma

NCT02225496

COMPLETED NA

Radium 223 in Castrate Resistant Prostate Cancer Bone Metastases

NCT02135484

TERMINATED Phase 1

MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy

NCT02089230

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Phase Distribution

PhaseTrial count
Phase 1 748
Phase 2 971
Phase 3 96
Phase 4 28

What is open in the M.D. Anderson Cancer Center pipeline

549 recruiting of 2,692 indexed (20% open); 1,201 completed (45%).

Phase mix: 124 late (III/IV) vs 1,719 early (I/II) (early-phase heavy).

Top condition: Hematopoietic and Lymphoid Cell Neoplasm (44 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.