Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 36 of 41
Investigation of Efficiency of Breathing With Different Breathing Patterns
NCT00784004
A Phase 1 Dose Escalating Trial of Bortezomib in Combination With Lenalidomide in Patients With Myelodysplasia
NCT00580242
Prevalence and Cardiovascular Effects of Growth Hormone Deficiency in Abdominal Obesity
NCT00562796
Invega (Paliperidone) for the Treatment of Mania in Children and Adolescents Ages 6-17 With Bipolar Disorder
NCT00592358
Endoscopic Mucosal Resection for the Diagnosis of a-Ganglionosis, a Controlled Prospective Trial (EDGE Trial)
NCT01515501
PET Study Examining the Dopaminergic Activity of Armodafinil in Adults
NCT00592943
Bone Marker Assessment of Multiple Myeloma Patients Treated With Aminobisphosphonates
NCT00577642
Intermittent Letrozole Therapy in Postmenopausal Women With Metastatic Breast Cancer
NCT00549822
Temsirolimus in Combination With Gemcitabine in Previously Untreated Metastatic Pancreatic Cancer
NCT00593008
Management of Incidentally Discovered Pancreatic Cysts
NCT00550108
Photochemical Tissue Bonding
NCT00586040
Evaluation of Adherence to Topical Agents: Applying Communication Technology to Improve Sunscreen Use
NCT00535769
Behavioral Medicine Intervention With Depressed Patients in a Community Health Center Setting
NCT01330420
Biomarkers to Predict CRT Response in Patients With HF (BIOCRT)
NCT01949246
A Randomized Controlled Trial of Using Video Images in Dementia
NCT00704886
Preoperative Cisplatin and Bevacizumab in ER-, PR-, HER2 Negative Breast Cancer
NCT00580333
Lifestyle Intervention to Improve Insulin Sensitivity and Markers of Cardiovascular Risk in Prostate Cancer Survivors
NCT00738140
Colorectal Cancer Screening Navigator Program for Low Income and Non-English Speaking Populations
NCT00476970
Cognitive-Behavior Therapy for Young Adults With Bipolar Disorder
NCT01176825
Clinical Effort Against Secondhand Smoke (CEASE) Program or Standard Care in Helping Parents Stop Smoking
NCT00664261
A Study of the Effects of Sarcosine on Symptoms and Brain Glycine Levels in People With Schizophrenia
NCT00538070
RAD001 in Advanced Hepatocellular Carcinoma
NCT00516165
Effectiveness of Acupuncture for Depressed Patients Taking Antidepressant Medications
NCT01633996
Dexmedetomidine Cardiovascular Safety in Pediatric Burn Patients
NCT00697788
hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects
NCT00742235
Effectiveness of Atomoxetine in Treating ADHD Symptoms in Children and Adolescents With Autism
NCT00498173
Comparison of Self and Clinician Administered Rating Scales in Patients With ADHD
NCT00711724
A Collaborative Care Program to Improve Depression Treatment in Cardiac Patients
NCT00847132
Late Effects of Proton Radiation Therapy in Patients With Low-Grade Glioma
NCT00681473
Cast Immobilization for Non-Displaced Scaphoid Fractures
NCT00916539
Hydroxychloroquine With or Without Erlotinib in Advanced Non-small Cell Lung Cancer (NSCLC)
NCT01026844
Intra-Operative Dural Brachytherapy With Yttrium-90 Plaque Applicators
NCT00706485
CBT for Adherence and Depression in Diabetes
NCT00564070
Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response
NCT00483223
Pain Study to See if Ultram ER Will Provide Relief to Subjects Whose Pain is Not Well Controlled by Narcotics
NCT00505531
A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol
NCT00709735
Sunitinib Tumor Levels in Patients Not on Enzyme-Inducing Anti-Epileptic Drugs Undergoing Debulking Surgery for Recurrent Glioblastoma
NCT00864864
Recombinant Hyaluronidase in Out-of-Hospital Setting: The EASI Access Trial
NCT00386386
Effects of TNF-alpha Antagonism (Etanercept) in Patients With the Metabolic Syndrome and Psoriasis
NCT00477191
HIV and Cardiovascular Risk
NCT00465426
Brief CBT for Anxiety and Advanced Cancer
NCT00706290
Blood Pressure Self Management for Hypertension & Prehypertension Using an Internet Enabled, Automated Self Management Program
NCT00786162
Study of the Effects of Mecamylamine and Varenicline in Schizophrenia
NCT00455650
Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism
NCT00452543
A Mammography FastTrack Program in Increasing the Number of Women Undergoing Breast Cancer Screening
NCT00462891
Safety Profile of Insulin Like Growth Factor-1 (IGF-I) Administration in Adolescents
NCT00516386
D-Cycloserine Enhancement of Exposure in Social Phobia
NCT00633984
Open-Label Pilot Study of Namenda in Adult Subjects With ADHD and ADHD NOS
NCT00586573
Two Approaches to Routine HIV Testing in a Hospital Emergency Department
NCT00502944
Effect of Losartan in Patients With Nonobstructive Hypertrophic Cardiomyopathy
NCT01150461
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.