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NCT04028414 · ClinicalTrials.gov registry record · NA
Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures
A NA study of Rehabilitation, sponsored by Major Extremity Trauma Research Consortium.
- Active
- Registry status
- NA
- Development phase
- 450
- Enrollment target
- 17
- Study locations
NCT04028414: Active NA study of Rehabilitation, sponsored by Major Extremity Trauma Research Consortium.
NCT04028414 is a NA study of Rehabilitation that is active but no longer recruiting, run by Major Extremity Trauma Research Consortium. The registered enrollment target is 450 participants, above the 135-participant average among 15 other Rehabilitation trials with a reported enrollment target (233% higher). The trial reports 17 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04028414, a NA study of Rehabilitation, is active but no longer recruiting, sponsored by Major Extremity Trauma Research Consortium.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 450 participants
- Enrollment target
- 17
- Study locations
Study Summary
The overall objective of this study is to compare outcomes following early versus delayed weight bearing for adult patients operatively treated for an ankle fracture without syndesmotic fixation. Additionally, early weight bearing will be tested in patients with unicondylar plateau fractures that do not involve joint impaction in the context of a pilot study.
Primary Outcome
Re-admissions for a limb related issue and all re-operations on the study limb will be prospectively tracked by the Research Coordinators by routinely scanning hospital admission and orthopaedic surgery logs to identify all admissions and same day surgeries of patients actively enrolled in the study. Complications include loss of reduction and hardware failure, infection, non-union, malunion and fusion.
Conditions Studied
Interventions
- OTHER Early Weight Bearing
Study Locations (17)
Maryland
- University of Maryland R Adams Cowley Shock Trauma Center - Baltimore
- Walter Reed National Military Medical Center - Bethesda
North Carolina
- Carolinas Medical Center - Charlotte
- Wake Forest Baptist Medical Center - Winston-Salem
Virginia
- University of Virginia - Charlottesville
- Inova Fairfax Hospital - Falls Church
Alabama
- University of Alabama at Birmingham - Birmingham
California
- University of California San Francisco Medical Center - San Francisco
Indiana
- Methodist Hospital - Indianapolis
Minnesota
- Hennepin County Medical Center / Regions Hospita - Minneapolis
New Hampshire
- Dartmouth-Hitchcock Medical Center - Lebanon
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 450 participants |
| Start Date | 2020-01-01 |
| Est. Completion | 2025-03 |
| Phase | NA |
What the registry record for NCT04028414 still lists
NCT04028414 is an interventional study that assigns participants to a tested intervention. The registered 450 participants enrollment target is mid-sized for trials with a published cap, above the 135-participant average among 15 other Rehabilitation trials with a reported enrollment target (233% higher).
The record links to 1 condition, with Rehabilitation appearing as the primary indexed condition, and to 1 intervention - of which Early Weight Bearing is the first listed.
NCT04028414 lists 17 locations in 14 states (Maryland, North Carolina, Virginia).
Frequently Asked Questions
What is clinical trial NCT04028414 about?
NCT04028414 is a clinical study titled "Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures". The overall objective of this study is to compare outcomes following early versus delayed weight bearing for adult patients operatively treated for an ankle fracture without syndesmotic fixation. Additionally, early weight bearing will be tested in patients with unicondylar plateau fractures that do...
What is the current status of trial NCT04028414?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 450 participants. The study started on 2020-01-01. Estimated completion is 2025-03.
What conditions does trial NCT04028414 study?
This clinical trial studies the following conditions: Rehabilitation.
What interventions are being tested in trial NCT04028414?
The interventions under investigation include: Early Weight Bearing (OTHER).
Who is sponsoring clinical trial NCT04028414?
This trial is sponsored by Major Extremity Trauma Research Consortium, which has 30 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04028414 being conducted?
This trial has 17 study locations across Alabama, California, Indiana, Maryland, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Rehabilitation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04028414's enrollment target sits among peer trials
450 2nd of 15 the highest of 15 other Rehabilitation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rehabilitation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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