Jazz Pharmaceuticals

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Jazz Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#212 of 15,742 sponsors by registered trial count).

128 total trials 15 currently recruiting 81 completed top decile by trial count

Jazz Pharmaceuticals: 128 sponsored US clinical trials, 15 recruiting.

Jazz Pharmaceuticals sponsors 128 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 81 completed. 50 of these trials are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Narcolepsy, with 5 trials.

Top-decile sponsor footprint

Jazz Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#212 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 27/100

81 of 108 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (75.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

128 total, page 2 of 3

TERMINATED Phase 3

Efficacy and Safety of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome

NCT03848832

COMPLETED Phase 3

A Multicenter Study of the Efficacy and Safety of JZP-258 in the Treatment of Idiopathic Hypersomnia (IH) With an Open-label Safety Extension

NCT03533114

COMPLETED Phase 1

A Trial to Evaluate the Potential Impact of Renal Impairment on the Pharmacokinetics and Safety of CPX-351

NCT03555955

COMPLETED

A Post-Marketing Observational Study of VYXEOS™

NCT03526926

TERMINATED Phase 2

ONC201 in Recurrent or Metastatic Type II Endometrial Cancer Endometrial Cancer

NCT03485729

COMPLETED Phase 2

CX-8998 for Absence Seizures

NCT03406702

COMPLETED Phase 2

An Open-Label Study of Defibrotide for the Prevention of Acute Graft-versus-Host-Disease (AGvHD)

NCT03339297

TERMINATED Phase 1

ONC201 in Pediatric H3 K27M Gliomas

NCT03416530

TERMINATED Phase 2

The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation

NCT03339401

TERMINATED Phase 2

ONC201 in Adults With Recurrent H3 K27M-mutant Glioma

NCT03295396

COMPLETED Phase 2

A Phase 2 RCT Study of CX-8998 for Essential Tremor

NCT03101241

COMPLETED Phase 3

Phase 3 Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms: Open-label Extension Phase (GWPCARE7)

NCT02954887

COMPLETED Phase 3

Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms (GWPCARE7)

NCT02953548

TERMINATED Phase 1

Oral ONC201 in Relapsed/Refractory Multiple Myeloma

NCT02863991

COMPLETED Phase 3

A Study of the Efficacy and Safety of JZP-258 in Subjects With Narcolepsy With Cataplexy

NCT03030599

COMPLETED Phase 2

A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

NCT03037203

COMPLETED Phase 1

Trial of ZW25 (Zanidatamab) in Patients With Advanced HER2-expressing Cancers

NCT02892123

COMPLETED Phase 3

Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients

NCT02851407

COMPLETED Phase 3

An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

NCT02544750

COMPLETED Phase 2

Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia

NCT02873338

COMPLETED Phase 3

A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

NCT02544763

TERMINATED Phase 2

Oral ONC201 in Adult Recurrent Glioblastoma

NCT02525692

TERMINATED Phase 3

A Phase 3 Study of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus Disease

NCT02439970

TERMINATED Phase 3

A Phase 3 Study of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus

NCT02439957

COMPLETED

A Web-based Observational Study of Patient-reported Outcomes in Adults With Narcolepsy

NCT02769780

COMPLETED Phase 3

Efficacy and Safety of GWP42003-P for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults

NCT02224560

COMPLETED Phase 3

"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"

NCT02348606

COMPLETED Phase 3

"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Narcolepsy"

NCT02348593

COMPLETED Phase 3

"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"

NCT02348619

COMPLETED Phase 3

"A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA"

NCT02348632

COMPLETED Phase 3

A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults

NCT02224690

COMPLETED Phase 3

GWPCARE2 A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome

NCT02224703

COMPLETED Phase 3

Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)

NCT02091375

TERMINATED

A Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304

NCT02420080

COMPLETED Phase 1

An Study to Evaluate the Effects of Fluconazole on the Pharmacokinetics (PK) of Sativex® in Healthy Subjects With Cannabis Experience.

NCT02325011

COMPLETED Phase 2

A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)

NCT02091206

COMPLETED Phase 3

A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy

NCT02221869

TERMINATED Phase 2

A Dose Confirmation and Pharmacokinetic Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young Adults With Acute Lymphoblastic Leukemia (ALL) /Lymphoblastic Lymphoma (LBL). Following Hypersensitivity to Pegaspargase (Oncaspar)

NCT02257684

COMPLETED Phase 2

An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients

NCT02238925

COMPLETED Phase 3

Study to Assess the Safety and Efficacy of Brincidofovir in Treatment of Early Versus Late Adenovirus Infection

NCT02087306

TERMINATED

The Chimerix CMX001 Registry

NCT02167685

COMPLETED Early Phase 1

Ph I Safety and Efficacy of ODSH in Patients Receiving Induction or Consolidation Therapy for Acute Myeloid Leukemia

NCT01843634

COMPLETED Phase 3

A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients

NCT01769170

COMPLETED Phase 1

Assessment of the Single Dose Pharmacokinetics and Tolerability of Sativex in Patients With Impaired Hepatic Function and Healthy Patients

NCT01887301

COMPLETED

Patient Registry of Intrathecal Ziconotide Management(PRIZM)

NCT01888120

COMPLETED Phase 3

Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia

NCT01696084

COMPLETED Phase 2

A Study of Erwinaze Administered Intravenously in Patients Who Had an Allergy to Frontline Asparaginase Therapy

NCT01643408

COMPLETED Phase 2

A Study of the Safety and Effectiveness of ADX-N05 for Excessive Daytime Sleepiness in Subjects With Narcolepsy

NCT01681121

COMPLETED Phase 2

A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness

NCT01485770

TERMINATED Phase 2

Phase 2 Study to Assess the Efficacy & Safety of Gemcitabine + Nab Paclitaxel With or Without Dociparstat in Metastatic Pancreatic Cancer Patients

NCT01461915

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What is open in the Jazz Pharmaceuticals pipeline

15 recruiting of 128 indexed (12% open); 81 completed (63%).

Phase mix: 50 late (III/IV) vs 69 early (I/II) (balanced across stages).

Top condition: Narcolepsy (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Jazz Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 128 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

Jazz Pharmaceuticals sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 10%20%30%40%50% Total trials Recruiting share Jazz PharmaceuticalsUniversity of Illinois at Urbana-ChampaignStony Brook UniversityRhode Island HospitalThe Methodist Hospital Research InstituteCochlearErchonia CorporationHutchmedInternational Maternal Pediatric Adolescent AIDS Clinical Trials Group
Jazz Pharmaceuticals sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Jazz Pharmaceuticals sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 128 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this Jazz Pharmaceuticals page

128 registered trials is a research-attention snapshot, not an endorsement of Jazz Pharmaceuticals or any single study.

  • 15 of Jazz Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Narcolepsy is the condition Jazz Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Narcolepsy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Jazz Pharmaceuticals pipeline card: 128 registered trials from official public datasets.Report a data error.