International AIDS Vaccine Initiative

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, International AIDS Vaccine Initiative sits in the top decile of US sponsors by registered trial count (#886 of 15,742 sponsors by registered trial count).

16 total trials 2 currently recruiting 13 completed early-phase tilt top decile by trial count

International AIDS Vaccine Initiative: 16 sponsored US clinical trials, 2 recruiting.

International AIDS Vaccine Initiative sponsors 16 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 13 completed. 0 of these trials are in Phase 3-4 (later-stage) and 16 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 1 trials.

Top-decile sponsor footprint

International AIDS Vaccine Initiative ranks in the top decile of sponsors by registered trial count (#886 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

A 90/100

13 of 13 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (100.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 1

A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health

NCT07565090

RECRUITING Phase 1

A Phase 1 Randomized, Observer-blind, Placebo-controlled, Dose-escalation Clinical Trial to Evaluate the Safety and Immunogenicity of rVSV∆G-MARV-GP Vaccine in Adults in Good General Health

NCT07425821

ACTIVE NOT RECRUITING Phase 1

A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core)

NCT05001373

COMPLETED Phase 1

Evaluation of Safety and Immunogenicity of rVSVΔG-SEBOV-GP Vaccine in Adults With Good General Health

NCT05724472

COMPLETED Phase 1

A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 Gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults

NCT04224701

COMPLETED Phase 1

Safety and Pharmacokinetics of the Combination Broadly Neutralizing Antibodies, 3BNC117-LS-J and 10-1074-LS-J, in Healthy American and African Adults

NCT04173819

COMPLETED Phase 1

A Randomized, Double-blinded, Placebo-controlled, Dose-escalation Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV Envelope Protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in Healthy, HIV-1 Uninfected Adults

NCT03699241

COMPLETED Phase 1

A Phase 1/2a Study of PGT121, VRC07-523LS and PGDM1400 Monoclonal Antibodies in HIV-uninfected and HIV-infected Adults

NCT03721510

COMPLETED Phase 1

A Phase I Trial to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted

NCT03547245

COMPLETED Phase 1

A Clinical Trial of PGDM1400 and PGT121 and VRC07-523LS Monoclonal Antibodies in HIV-infected and HIV-uninfected Adults

NCT03205917

COMPLETED Phase 1

Safety, PK and Antiviral Activity of PGT121 Monoclonal Antibody in HIV-uninfected and HIV-infected Adults

NCT02960581

COMPLETED Phase 1

Trial of the Safety and Immunogenicity of an Oral, Replicating Ad26 Vectored HIV-1 Vaccine

NCT02366013

COMPLETED Phase 1

Safety and Immunogenicity Study of Ad26-ENVA and Ad35-ENV HIV Vaccines in Healthy HIV-uninfected Adults

NCT01215149

COMPLETED Phase 1

A Trial to Evaluate Ad35-GRIN/ENV HIV Vaccine in Healthy Adult Volunteers

NCT00851383

COMPLETED Phase 1

Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA) HIV Vaccine in HIV Uninfected Adults

NCT00252148

COMPLETED Phase 1

Safety and Immunogenicity of a Plasmid HIV Vaccine in HIV Uninfected Adults

NCT00249106

Phase Distribution

PhaseTrial count
Phase 1 16

Therapeutic Areas

What is open in the International AIDS Vaccine Initiative pipeline

2 recruiting of 16 indexed (13% open); 13 completed (81%).

Phase mix: 0 late (III/IV) vs 16 early (I/II) (early-phase heavy).

Top condition: HIV Infections (1 trial), 2 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

International AIDS Vaccine Initiative: open-pipeline peers nationwide

Peers matched on 16 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

International AIDS Vaccine Initiative sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 681012141618 0%5%10%15% Total trials Recruiting share International AIDS Vaccine InitiativeAccelerated Community Oncology Research NetworkAltimmuneAmerican UniversityAnthera PharmaceuticalsAddario Lung Cancer Medical InstituteAnnexonAnsun BiopharmaAvidity Biosciences
International AIDS Vaccine Initiative sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

International AIDS Vaccine Initiative sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 16 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this International AIDS Vaccine Initiative page

16 registered trials is a research-attention snapshot, not an endorsement of International AIDS Vaccine Initiative or any single study.

  • 2 of International AIDS Vaccine Initiative's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition International AIDS Vaccine Initiative studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

International AIDS Vaccine Initiative pipeline card: 16 registered trials from official public datasets.Report a data error.