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NCT05001373 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core)
A Phase 1 study of HIV, sponsored by International AIDS Vaccine Initiative.
- Active
- Registry status
- Phase 1
- Development phase
- 56
- Enrollment target
- 4
- Study locations
NCT05001373: Active Phase 1 study of HIV, sponsored by International AIDS Vaccine Initiative.
NCT05001373 is a Phase 1 study of HIV that is active but no longer recruiting, run by International AIDS Vaccine Initiative. The registered enrollment target is 56 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (87% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05001373, a Phase 1 study of HIV, is active but no longer recruiting, sponsored by International AIDS Vaccine Initiative.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 56 participants
- Enrollment target
- 4
- Study locations
Study Summary
A Phase 1, Randomized, First-in-human, Open-label Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core) in HIV-1 Uninfected Adults in Good General Health
Conditions Studied
Interventions
- BIOLOGICAL Core-g28v2 60mer mRNA Vaccine
- BIOLOGICAL eOD-GT8 60mer mRNA Vaccine
Study Locations (4)
District of Columbia
- George Washington University - Washington D.C.
Georgia
- Emory University - Atlanta
Texas
- UT Health San Antonio - San Antonio
Washington
- Fred Hutchinson Cancer Research Center - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2021-11-12 |
| Est. Completion | 2024-07-01 |
| Phase | Phase 1 |
What the registry record for NCT05001373 still lists
NCT05001373 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 440-participant average among 303 other HIV trials with a reported enrollment target (87% lower).
The record links to 1 condition, with HIV appearing as the primary indexed condition, and to 2 interventions - of which Core-g28v2 60mer mRNA Vaccine is the first listed.
NCT05001373 reports a single indexed study location in District of Columbia, Georgia, Texas.
Frequently Asked Questions
What is clinical trial NCT05001373 about?
NCT05001373 is a clinical study titled "A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core)". A Phase 1, Randomized, First-in-human, Open-label Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core) in HIV-1 Uninfected Adults in Good General Health
What is the current status of trial NCT05001373?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 56 participants. The study started on 2021-11-12. Estimated completion is 2024-07-01.
What conditions does trial NCT05001373 study?
This clinical trial studies the following conditions: HIV.
What interventions are being tested in trial NCT05001373?
The interventions under investigation include: Core-g28v2 60mer mRNA Vaccine (BIOLOGICAL), eOD-GT8 60mer mRNA Vaccine (BIOLOGICAL).
Who is sponsoring clinical trial NCT05001373?
This trial is sponsored by International AIDS Vaccine Initiative, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05001373 being conducted?
This trial has 4 study locations across District of Columbia, Georgia, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT05001373's enrollment target sits among peer trials
56 207th of 303 higher than 96 of 303 other HIV trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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