Geron Corporation

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Geron Corporation sits in the top decile of US sponsors by registered trial count (#934 of 15,742 sponsors by registered trial count).

15 total trials 1 currently recruiting 12 completed early-phase tilt top decile by trial count

Geron Corporation: 15 sponsored US clinical trials, 1 recruiting.

Geron Corporation sponsors 15 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 12 completed. 1 of these trials are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Multiple Myeloma, with 3 trials.

Top-decile sponsor footprint

Geron Corporation ranks in the top decile of sponsors by registered trial count (#934 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

A 90/100

12 of 12 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (100.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

15 total, page 1 of 1

RECRUITING Phase 1

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

NCT05371964

ACTIVE NOT RECRUITING Phase 3

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

NCT04576156

ACTIVE NOT RECRUITING Phase 2

Study to Evaluate Imetelstat (GRN163L) in Participants With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

NCT02598661

COMPLETED Phase 2

Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor

NCT02426086

COMPLETED Phase 2

Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis

NCT01731951

COMPLETED Phase 2

Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera

NCT01243073

COMPLETED Phase 2

Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma

NCT01242930

COMPLETED Phase 2

Imetelstat in Combination With Paclitaxel (With or Without Bevacizumab) in Patients With Locally Recurrent or Metastatic Breast Cancer

NCT01256762

COMPLETED Phase 2

Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)

NCT01137968

COMPLETED Phase 1

Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed Myeloma

NCT00718601

COMPLETED Phase 1

A Study of GRN163L With Paclitaxel and Bevacizumab to Treat Patients With Locally Recurrent Or Metastatic Breast Cancer

NCT00732056

COMPLETED Phase 1

Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma

NCT00594126

COMPLETED Phase 1

Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer

NCT00510445

COMPLETED Phase 1

Safety and Dose Study of GRN163L Administered to Patients With Refractory or Relapsed Solid Tumor Malignancies

NCT00310895

COMPLETED Phase 1

Safety and Dose Study of GRN163L to Treat Patients With Chronic Lymphoproliferative Disease(CLD)

NCT00124189

What is open in the Geron Corporation pipeline

1 recruiting of 15 indexed (7% open); 12 completed (80%).

Phase mix: 1 late (III/IV) vs 14 early (I/II) (early-phase heavy).

Top condition: Multiple Myeloma (3 trials), 6 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Geron Corporation: open-pipeline peers nationwide

Peers matched on 15 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

Geron Corporation sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 14.914.91515.1 0%10%20%30%40% Total trials Recruiting share Geron CorporationAllakosArbor Research Collaborative for HealthArena PharmaceuticalsArrowhead PharmaceuticalsBaylor Breast Care CenterGuerbetJoanne Kurtzberg, MDLakefront Biotherapeutics
Geron Corporation sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Geron Corporation sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 15 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this Geron Corporation page

15 registered trials is a research-attention snapshot, not an endorsement of Geron Corporation or any single study.

  • 1 of Geron Corporation's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Multiple Myeloma is the condition Geron Corporation studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Multiple Myeloma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Geron Corporation pipeline card: 15 registered trials from official public datasets.Report a data error.