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NCT02426086 · ClinicalTrials.gov registry record · Phase 2

Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor

A Phase 2 study, sponsored by Geron Corporation.

Completed
Registry status
Phase 2
Development phase
107
Enrollment target

NCT02426086 is a Phase 2 study that has completed, run by Geron Corporation. The registered enrollment target is 107 participants.

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The verdict

NCT02426086, a Phase 2 study, has completed, sponsored by Geron Corporation.

COMPLETED
Registry status
Phase 2
Development phase
107 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the efficacy and safety of 2 dose regimens of imetelstat in participants with intermediate-2 or high-risk myelofibrosis (MF) whose disease is relapsed after or is refractory to Janus Kinase (JAK) inhibitor treatment. Key secondary endpoint includes overall survival.

Interventions

  • DRUG Imetelstat 4.7 mg/kg
  • DRUG Imetelstat 9.4 mg/kg

Trial Details

FieldValue
Enrollment Target 107 participants
Start Date 2015-08-28
Est. Completion 2020-02-07
Phase Phase 2

Sponsor

Geron Corporation

15 total trials

What the Registry Record Tells You About NCT02426086

The ClinicalTrials.gov registry entry for NCT02426086 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 107 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Geron Corporation, which has 15 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Imetelstat 4.7 mg/kg is the first listed.

NCT02426086 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02426086 about?

NCT02426086 is a clinical study titled "Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor". The purpose of this study is to evaluate the efficacy and safety of 2 dose regimens of imetelstat in participants with intermediate-2 or high-risk myelofibrosis (MF) whose disease is relapsed after or is refractory to Janus Kinase (JAK) inhibitor treatment. Key secondary endpoint includes overall su...

What is the current status of trial NCT02426086?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 107 participants. The study started on 2015-08-28. Estimated completion is 2020-02-07.

What interventions are being tested in trial NCT02426086?

The interventions under investigation include: Imetelstat 4.7 mg/kg (DRUG), Imetelstat 9.4 mg/kg (DRUG).

Who is sponsoring clinical trial NCT02426086?

This trial is sponsored by Geron Corporation, which has 15 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.