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NCT00718601 · ClinicalTrials.gov registry record · Phase 1

Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed Myeloma

A Phase 1 study of Multiple Myeloma, sponsored by Geron Corporation.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target
3
Study locations

NCT00718601 is a Phase 1 study of Multiple Myeloma that has completed, run by Geron Corporation. The registered enrollment target is 40 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (93% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT00718601, a Phase 1 study of Multiple Myeloma, has completed, sponsored by Geron Corporation.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target
3
Study locations

Study Summary

The purpose of this study is to determine safety and the maximum tolerated dose (MTD) of GRN163L and Velcade with and without Decadron when administered to patients with refractory or relapsed multiple myeloma.

Conditions Studied

Interventions

  • DRUG Imetelstat Sodium (GRN163L)

Study Locations (3)

Michigan

  • Karmanos Cancer Center - Detroit

New York

  • St. Vincent's Comprehensive Cancer Center - New York

Washington

  • Fred Hutchinson Cancer Research Center - Seattle

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2008-07
Est. Completion 2011-10
Phase Phase 1

Sponsor

Geron Corporation

15 total trials

What the Registry Record Tells You About NCT00718601

The ClinicalTrials.gov registry entry for NCT00718601 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (93% lower). The listed sponsor is Geron Corporation, which has 15 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 1 intervention - of which Imetelstat Sodium (GRN163L) is the first listed.

NCT00718601 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Michigan, New York, Washington.

Frequently Asked Questions

What is clinical trial NCT00718601 about?

NCT00718601 is a clinical study titled "Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed Myeloma". The purpose of this study is to determine safety and the maximum tolerated dose (MTD) of GRN163L and Velcade with and without Decadron when administered to patients with refractory or relapsed multiple myeloma.

What is the current status of trial NCT00718601?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2008-07. Estimated completion is 2011-10.

What conditions does trial NCT00718601 study?

This clinical trial studies the following conditions: Multiple Myeloma.

What interventions are being tested in trial NCT00718601?

The interventions under investigation include: Imetelstat Sodium (GRN163L) (DRUG).

Who is sponsoring clinical trial NCT00718601?

This trial is sponsored by Geron Corporation, which has 15 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00718601 being conducted?

This trial has 3 study locations across Michigan, New York, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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