Genzyme, a Sanofi Company
Genzyme, a Sanofi Company sponsors 196 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 159 completed. 65 of these trials are in Phase 3-4 (later-stage) and 114 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Glycogen Storage Disease Type II (GSD-II), with 5 trials.
Trial Pipeline
196 total, page 1 of 4
Pompe Pregnancy Sub-Registry
NCT00567073
Pompe Disease Registry Protocol
NCT00231400
Fabry Disease Registry & Pregnancy Sub-registry
NCT00196742
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
NCT00358943
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B
NCT03974113
Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX
NCT03754790
A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patients With Infantile-onset Pompe Disease Previously Treated With Alglucosidase Alfa
NCT03019406
Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy Extension
NCT02843035
A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2
NCT04221451
Study of Lademirsen (SAR339375) in Patients With Alport Syndrome
NCT02855268
Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada
NCT03784898
Effect of Venglustat in Patients With Renal Impairment
NCT03687554
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients
NCT03523728
A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants
NCT06421714
A Study of Fitusiran in Severe Hemophilia A and B Patients Previously Receiving Factor or Bypassing Agent Prophylaxis
NCT03549871
A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients Without Inhibitors
NCT03417245
A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors
NCT03417102
A Study of RG-012 in Subjects With Alport Syndrome
NCT03373786
A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation
NCT02906020
Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease
NCT02782741
Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency
NCT02004691
An Open-label Extension Study of an Investigational Drug, Fitusiran, in Patients With Moderate or Severe Hemophilia A or B
NCT02554773
LEMTRADA Pregnancy Registry in Multiple Sclerosis
NCT03774914
A Study of the Effects of Hepatic Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate
NCT02536911
Evaluation of the Long-term Safety, Pharmacodynamics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-Naïve Adult Male Patients With Fabry Disease
NCT02489344
Safety, Tolerability, PK, and Efficacy Evaluation of Repeat Ascending Doses of Olipudase Alfa in Pediatric Patients <18 Years of Age With Acid Sphingomyelinase Deficiency
NCT02292654
Taste Evaluation of Different Liquid Formulations With Eliglustat
NCT02422654
Alglucosidase Alfa Pompe Safety Sub-Registry
NCT01710813
Efficacy and Safety of Vatelizumab in Patients Who Completed Treatment in Study DRI13839
NCT02306811
Phase IIIB-IV Long-Term Follow-up Study for Patients Who Participated in CAMMS03409
NCT02255656
Pharmacokinetics of Alglucosidase Alfa in Patients With Pompe Disease
NCT01410890
Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-naïve Adult Male Patients With Fabry Disease
NCT02228460
ATHENA: Natural History of Disease Study in Alport Syndrome Patients
NCT02136862
Efficacy and Safety of Vatelizumab in Patients With Relapsing-Remitting Multiple Sclerosis
NCT02222948
Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis
NCT02201108
Avalglucosidase Alfa Extension Study
NCT02032524
A Long-Term Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency
NCT02004704
Evaluation of Efficacy, Safety of Vandetanib in Patients With Differentiated Thyroid Cancer
NCT01876784
Safety and Efficacy Evaluation of Repeat neoGAA Dosing in Late Onset Pompe Disease Patients.
NCT01898364
A Study of Renal Function in Treatment-naïve, Young Male Patients With Fabry Disease
NCT01839526
Tolerability and Safety Study of Recombinant Human Acid Sphingomyelinase in Acid Sphingomyelinase Deficiency Patients
NCT01722526
A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of Genz-682452 in Healthy Volunteers
NCT01710826
A Study of the Safety and Effectiveness of Synvisc-One® (Hylan G-F 20) in Patients With Primary Osteoarthritis of the Hip
NCT01618708
Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men
NCT01674036
A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS)
NCT01665391
A Noninferiority Study of Alglucosidase Alfa Manufactured at the 160 L and 4000 L Scales in Treatment Naïve Patients With Infantile-Onset Pompe Disease
NCT01597596
Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults
NCT01659944
An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Disease
NCT01574326
A Study Evaluating Glycosphingolipid Clearance in Patients Treated With Agalsidase Alfa Who Switch to Agalsidase Beta
NCT01650779
Pompe Lactation Sub-Registry
NCT00566878
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 48 |
| Phase 2 | 66 |
| Phase 3 | 40 |
| Phase 4 | 25 |
Therapeutic Areas
What the Pipeline for Genzyme, a Sanofi Company Shows
According to the ClinicalTrials.gov registry, Genzyme, a Sanofi Company is linked to 196 US clinical trials across every stage of research activity. Of those, 4 studies are currently recruiting, about 2% of the sponsor's indexed portfolio, and 159 are already marked complete, representing roughly 81% of the total.
The phase mix for Genzyme, a Sanofi Company reports 65 late-stage studies (Phase 3 and Phase 4 combined) and 114 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Genzyme, a Sanofi Company is Glycogen Storage Disease Type II (GSD-II) with 5 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.