ECOG-ACRIN Cancer Research Group

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, ECOG-ACRIN Cancer Research Group sits in the top decile of US sponsors by registered trial count (#290 of 15,742 sponsors by registered trial count).

75 total trials 12 currently recruiting 16 completed early-phase tilt top decile by trial count

ECOG-ACRIN Cancer Research Group: 75 sponsored US clinical trials, 12 recruiting.

ECOG-ACRIN Cancer Research Group sponsors 75 registered US clinical trials on ClinicalTrials.gov, 12 of them currently recruiting, and 16 completed. 23 of these trials are in Phase 3-4 (later-stage) and 35 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Invasive Breast Carcinoma, with 3 trials.

Top-decile sponsor footprint

ECOG-ACRIN Cancer Research Group ranks in the top decile of sponsors by registered trial count (#290 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 0/100

16 of 26 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (61.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

75 total, page 2 of 2

TERMINATED Phase 2

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

NCT04527549

TERMINATED Phase 2

Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

NCT04438382

COMPLETED NA

Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices

NCT03808818

TERMINATED NA

Perfusion CT in Predicting Outcomes in Ovarian, Fallopian, or Peritoneal Cancer With Bevacizumab

NCT03412630

COMPLETED NA

Pre-Test Genetic Education and Remote Genetic Counseling in Communicating Tumor Profiling Results to Patients With Advanced Cancer

NCT02823652

COMPLETED Phase 2

Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer

NCT02412670

TERMINATED Phase 2

Afatinib After Chemoradiation and Surgery in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck at High-Risk of Recurrence

NCT01824823

TERMINATED Phase 2

Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery

NCT02031536

COMPLETED Phase 1

Docetaxel With or Without FGFR Inhibitor AZD4547 in Treating Patients With Recurrent Non-Small Cell Lung Cancer

NCT01824901

TERMINATED Phase 2

Chemotherapy Based on PET Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma

NCT01390584

TERMINATED Phase 2

Rituximab and Alemtuzumab in Treating Older Patients With Progressive Chronic Lymphocytic Leukemia

NCT01013961

COMPLETED Phase 2

Bendamustine Hydrochloride and Rituximab With or Without Bortezomib Followed by Rituximab With or Without Lenalidomide in Treating Patients With High-Risk Stage II, Stage III, or Stage IV Follicular Lymphoma

NCT01216683

COMPLETED Phase 3

Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02085408

COMPLETED Phase 2

BLP25 Liposome Vaccine and Bevacizumab After Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

NCT00828009

COMPLETED Phase 2

Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer

NCT01124695

COMPLETED Phase 3

Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer

NCT01107626

COMPLETED Phase 2

Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By Surgery

NCT01164228

COMPLETED Phase 2

Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer

NCT00316888

COMPLETED Phase 3

Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer

NCT00309985

TERMINATED Phase 3

Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal Cancer

NCT00303628

COMPLETED Phase 3

Levocarnitine in Treating Fatigue in Cancer Patients

NCT00091169

COMPLETED Phase 3

Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer

NCT00008385

COMPLETED Phase 2

Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Gastric Cancer

NCT00003298

COMPLETED

Analysis of Tumor Tissue and Lymph Nodes Surgically Removed From Patients With Cancers of the Head and Neck

NCT00002695

TERMINATED Phase 3

Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed

NCT00002525

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What is open in the ECOG-ACRIN Cancer Research Group pipeline

12 recruiting of 75 indexed (16% open); 16 completed (21%).

Phase mix: 23 late (III/IV) vs 35 early (I/II) (early-phase heavy).

Top condition: Invasive Breast Carcinoma (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

ECOG-ACRIN Cancer Research Group: open-pipeline peers nationwide

Peers matched on 75 registered trials and 16% open enrollment, not the therapeutic-area sidebar.

ECOG-ACRIN Cancer Research Group sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 0%10%20%30%40% Total trials Recruiting share ECOG-ACRIN Cancer Research GroupC. R. BardHartford HospitalInova Health Care ServicesIonis PharmaceuticalsGeorge Mason UniversityUniversity of ArizonaUniversity of California, San FranciscoUniversity of Oregon
ECOG-ACRIN Cancer Research Group sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

ECOG-ACRIN Cancer Research Group sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 75 trials (± recruiting share)

Sponsors near 16% open enrollment (± trial volume)

What to do with this ECOG-ACRIN Cancer Research Group page

75 registered trials is a research-attention snapshot, not an endorsement of ECOG-ACRIN Cancer Research Group or any single study.

  • 12 of ECOG-ACRIN Cancer Research Group's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Invasive Breast Carcinoma is the condition ECOG-ACRIN Cancer Research Group studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Invasive Breast Carcinoma trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

ECOG-ACRIN Cancer Research Group pipeline card: 75 registered trials from official public datasets.Report a data error.