Centessa Pharmaceuticals (UK) Limited

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Centessa Pharmaceuticals (UK) Limited sits in the upper quartile of US sponsors by registered trial count (#2,085 of 15,742 sponsors by registered trial count).

6 total trials 5 currently recruiting early-phase tilt upper quartile by trial count

Centessa Pharmaceuticals (UK) Limited: 6 sponsored US clinical trials, 5 recruiting.

Centessa Pharmaceuticals (UK) Limited sponsors 6 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting. 0 of these trials are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Narcolepsy Type 1, with 2 trials.

Upper-quartile sponsor footprint

Centessa Pharmaceuticals (UK) Limited sits in the upper quartile of the sponsor corpus (#2,085 of 15,742 sponsors by registered trial count) - denser than most sponsors, still short of the top-decile hubs.

Open and recent trials

6 total, page 1 of 1

RECRUITING Phase 2

A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence

NCT07598708
RECRUITING Phase 1

A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years

NCT07413666
RECRUITING Phase 2

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

NCT07096674
RECRUITING Phase 1

A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

NCT07082829
RECRUITING Phase 2

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

NCT06752668
TERMINATED Phase 1

A Study to Evaluate Safety, Tolerability and Preliminary Activity of LB101 in Participants With Advanced Solid Tumors

NCT05821777

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3

Therapeutic Areas

Narcolepsy Type 1 2
Idiopathic Hypersomnia 2
Narcolepsy Type 2 2
Excessive Daytime Sleepiness 1
Healthy Adult Male and Female Volunteers 1

What is open in the Centessa Pharmaceuticals (UK) Limited pipeline

5 recruiting of 6 indexed (83% open).

Phase mix: 0 late (III/IV) vs 6 early (I/II) (early-phase heavy).

Top condition: Narcolepsy Type 1 (2 trials), 4 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Centessa Pharmaceuticals (UK) Limited: open-pipeline peers nationwide

Peers matched on 6 registered trials and 83% open enrollment, not the therapeutic-area sidebar.

Centessa Pharmaceuticals (UK) Limited sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 5.566.577.5 0%20%40%60%80%100% Total trials Recruiting share Centessa Pharmaceuticals (UK) Limited23andMeAardvark TherapeuticsAbbisko Therapeutics CoAbGenomics B.V Taiwan BranchMeyer Children's Hospital IRCCSSystImmuneTyra BiosciencesJohnson & Johnson Enterprise Innovation
Centessa Pharmaceuticals (UK) Limited sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Centessa Pharmaceuticals (UK) Limited sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 6 trials (± recruiting share)

Sponsors near 83% open enrollment (± trial volume)

Related

Read our methodology - how this data is sourced, computed, and verified.

What to do with this Centessa Pharmaceuticals (UK) Limited page

6 registered trials is a research-attention snapshot, not an endorsement of Centessa Pharmaceuticals (UK) Limited or any single study.

  • 5 of Centessa Pharmaceuticals (UK) Limited's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Narcolepsy Type 1 is the condition Centessa Pharmaceuticals (UK) Limited studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Narcolepsy Type 1 trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Centessa Pharmaceuticals (UK) Limited pipeline card: 6 registered trials from official public datasets.Report a data error.