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NCT07413666 · ClinicalTrials.gov registry record · Phase 1

A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years

A Phase 1 study of Healthy Adult Male and Female Volunteers, sponsored by Centessa Pharmaceuticals (UK) Limited.

Recruiting
Registry status
Phase 1
Development phase
212
Enrollment target
1
Study location

NCT07413666 is a Phase 1 study of Healthy Adult Male and Female Volunteers that is actively recruiting participants, run by Centessa Pharmaceuticals (UK) Limited. The registered enrollment target is 212 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT07413666, a Phase 1 study of Healthy Adult Male and Female Volunteers, is actively recruiting participants, sponsored by Centessa Pharmaceuticals (UK) Limited.

RECRUITING
Registry status
Phase 1
Development phase
212 participants
Enrollment target
1
Study location

Study Summary

Characterize the safety, tolerability and pharmacokinetics of ORX489 following single and multiple doses.

Interventions

  • DRUG ORX489 Tablets
  • OTHER Placebo Tablets

Study Locations (1)

Nebraska

  • Celerion - Lincoln

Trial Details

FieldValue
Enrollment Target 212 participants
Start Date 2026-02-25
Est. Completion 2027-06-30
Phase Phase 1

What the Registry Record Tells You About NCT07413666

The ClinicalTrials.gov registry entry for NCT07413666 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 212 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Centessa Pharmaceuticals (UK) Limited, which has 6 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Adult Male and Female Volunteers appearing as the primary indexed condition, and to 2 interventions - of which ORX489 Tablets is the first listed.

NCT07413666 reports 1 study location spanning 1 distinct geographic area - top geographies include Nebraska.

Frequently Asked Questions

What is clinical trial NCT07413666 about?

NCT07413666 is a clinical study titled "A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years". Characterize the safety, tolerability and pharmacokinetics of ORX489 following single and multiple doses.

What is the current status of trial NCT07413666?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 212 participants. The study started on 2026-02-25. Estimated completion is 2027-06-30.

What conditions does trial NCT07413666 study?

This clinical trial studies the following conditions: Healthy Adult Male and Female Volunteers.

What interventions are being tested in trial NCT07413666?

The interventions under investigation include: ORX489 Tablets (DRUG), Placebo Tablets (OTHER).

Who is sponsoring clinical trial NCT07413666?

This trial is sponsored by Centessa Pharmaceuticals (UK) Limited, which has 6 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07413666 being conducted?

This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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