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NCT07082829 · ClinicalTrials.gov registry record · Phase 1
A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age
A Phase 1 study of Excessive Daytime Sleepiness, sponsored by Centessa Pharmaceuticals (UK) Limited.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 208
- Enrollment target
- 3
- Study locations
NCT07082829 is a Phase 1 study of Excessive Daytime Sleepiness that is actively recruiting participants, run by Centessa Pharmaceuticals (UK) Limited. The registered enrollment target is 208 participants, above the 112-participant average among 3 other Excessive Daytime Sleepiness trials with a reported enrollment target (86% higher). The trial reports 3 study locations across 3 states.
The verdict
NCT07082829, a Phase 1 study of Excessive Daytime Sleepiness, is actively recruiting participants, sponsored by Centessa Pharmaceuticals (UK) Limited.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 208 participants
- Enrollment target
- 3
- Study locations
Study Summary
Characterize the safety, tolerability and pharmacokinetics of ORX142 following single and multiple doses.
Conditions Studied
Interventions
- OTHER Placebo Tablets
- DRUG ORX142 Tablets
Study Locations (3)
Nebraska
- Site #1 - Lincoln
New Jersey
- Site #2 - Eatontown
New York
- Site #3 - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 208 participants |
| Start Date | 2025-06-30 |
| Est. Completion | 2026-06-15 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07082829
The ClinicalTrials.gov registry entry for NCT07082829 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 208 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 112-participant average among 3 other Excessive Daytime Sleepiness trials with a reported enrollment target (86% higher). The listed sponsor is Centessa Pharmaceuticals (UK) Limited, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Excessive Daytime Sleepiness appearing as the primary indexed condition, and to 2 interventions - of which Placebo Tablets is the first listed.
NCT07082829 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Nebraska, New Jersey, New York.
Frequently Asked Questions
What is clinical trial NCT07082829 about?
NCT07082829 is a clinical study titled "A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age". Characterize the safety, tolerability and pharmacokinetics of ORX142 following single and multiple doses.
What is the current status of trial NCT07082829?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 208 participants. The study started on 2025-06-30. Estimated completion is 2026-06-15.
What conditions does trial NCT07082829 study?
This clinical trial studies the following conditions: Excessive Daytime Sleepiness.
What interventions are being tested in trial NCT07082829?
The interventions under investigation include: Placebo Tablets (OTHER), ORX142 Tablets (DRUG).
Who is sponsoring clinical trial NCT07082829?
This trial is sponsored by Centessa Pharmaceuticals (UK) Limited, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07082829 being conducted?
This trial has 3 study locations across Nebraska, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.