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NCT05821777 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate Safety, Tolerability and Preliminary Activity of LB101 in Participants With Advanced Solid Tumors
A Phase 1 study, sponsored by Centessa Pharmaceuticals (UK) Limited.
- Terminated
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
NCT05821777: Clinical Trial Phase 1 study, sponsored by Centessa Pharmaceuticals (UK) Limited.
NCT05821777 is a Phase 1 study that was terminated before completion, run by Centessa Pharmaceuticals (UK) Limited. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05821777, a Phase 1 study, was terminated before completion, sponsored by Centessa Pharmaceuticals (UK) Limited.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
The purpose of this study is to assess safety, tolerability, and preliminary activity of LB101 monotherapy in participants with advanced solid tumors.
Interventions
- DRUG LB101
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2023-03-28 |
| Est. Completion | 2025-09-09 |
| Phase | Phase 1 |
Why NCT05821777 stopped before completion
NCT05821777 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).
The record links to 0 conditions, and to 1 intervention - of which LB101 is the first listed.
NCT05821777 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05821777 about?
NCT05821777 is a clinical study titled "A Study to Evaluate Safety, Tolerability and Preliminary Activity of LB101 in Participants With Advanced Solid Tumors". The purpose of this study is to assess safety, tolerability, and preliminary activity of LB101 monotherapy in participants with advanced solid tumors.
What is the current status of trial NCT05821777?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2023-03-28. Estimated completion is 2025-09-09.
What interventions are being tested in trial NCT05821777?
The interventions under investigation include: LB101 (DRUG).
Who is sponsoring clinical trial NCT05821777?
This trial is sponsored by Centessa Pharmaceuticals (UK) Limited, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05821777's enrollment target sits among peer trials
25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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