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NCT06989775 · ClinicalTrials.gov registry record · NA
BoxX-NoAF Clinical Trial
A NA study of Post Operative Atrial Fibrillation and Atrial Fibrillation, Postoperative, sponsored by AtriCure.
- Recruiting
- Registry status
- NA
- Development phase
- 960
- Enrollment target
- 10
- Study locations
NCT06989775: Recruiting NA study of Post Operative Atrial Fibrillation and Atrial Fibrillation, Postoperative, sponsored by AtriCure.
NCT06989775 is a NA study of Post Operative Atrial Fibrillation and Atrial Fibrillation, Postoperative that is actively recruiting participants, run by AtriCure. The registered enrollment target is 960 participants, above the 394-participant average among 5 other Post Operative Atrial Fibrillation trials with a reported enrollment target (144% higher). The trial reports 10 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06989775, a NA study of Post Operative Atrial Fibrillation and Atrial Fibrillation, Postoperative, is actively recruiting participants, sponsored by AtriCure.
- RECRUITING
- Registry status
- NA
- Development phase
- 960 participants
- Enrollment target
- 10
- Study locations
Study Summary
Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline characteristics and surgery type. Patients with POAF tend to have worse acute and long-term clinical outcomes. BoxX-NoAF is a randomized trial to evaluate if prophylactic ablation and exclusion of the Left Atrial Appendage at the time of other routine cardiac surgery can reduce the incidence of post operative AF and clinical AF during long term follow up in patients who have not yet developed AF but are at risk.
Primary Outcome
The occurrence of clinically relevant post operative AF (POAF)
Conditions Studied
Interventions
- DEVICE Isolator® Synergy™ EnCompass® Ablation System and AtriClip® LAA Exclusion System
Study Locations (10)
Florida
- Morton Plant Hospital - BayCare Health System, Inc. - Clearwater
- St. Joseph's Hospital - BayCare Health System, Inc. - Clearwater
- Orlando Health, Inc. - Orlando
Arkansas
- St. Bernards Medical Center - Jonesboro
Georgia
- Wellstar Health System - Marietta
Michigan
- Corewell Health - Grand Rapids
Minnesota
- Mayo Clinic - Rochester
New York
- New York Presbyterian Hospital/Columbia University Irving Medical Center - New York
Tennessee
- Ascension Saint Thomas - Nashville
Ontario
- Hamilton General Hospital - Hamilton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 960 participants |
| Start Date | 2025-10-24 |
| Est. Completion | 2031-11 |
| Phase | NA |
What NCT06989775 shows while recruiting
NCT06989775 is an interventional study that assigns participants to a tested intervention. The registered 960 participants enrollment target is mid-sized for trials with a published cap, above the 394-participant average among 5 other Post Operative Atrial Fibrillation trials with a reported enrollment target (144% higher).
The record links to 2 conditions, with Post Operative Atrial Fibrillation appearing as the primary indexed condition, and to 1 intervention - of which Isolator® Synergy™ EnCompass® Ablation System and AtriClip® LAA Exclusion System is the first listed.
NCT06989775 lists 10 locations in 8 states (Florida, Arkansas, Georgia).
Frequently Asked Questions
What is clinical trial NCT06989775 about?
NCT06989775 is a clinical study titled "BoxX-NoAF Clinical Trial". Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline characteristics and surgery type. Patients with POAF tend to have worse acute and long-term clinical outcomes. BoxX-NoAF is a randomized trial...
What is the current status of trial NCT06989775?
This trial is currently recruiting. It is a NA study. The enrollment target is 960 participants. The study started on 2025-10-24. Estimated completion is 2031-11.
What conditions does trial NCT06989775 study?
This clinical trial studies the following conditions: Post Operative Atrial Fibrillation, Atrial Fibrillation, Postoperative.
What interventions are being tested in trial NCT06989775?
The interventions under investigation include: Isolator® Synergy™ EnCompass® Ablation System and AtriClip® LAA Exclusion System (DEVICE).
Who is sponsoring clinical trial NCT06989775?
This trial is sponsored by AtriCure, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06989775 being conducted?
This trial has 10 study locations across Arkansas, Florida, Georgia, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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