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NCT02160626 · ClinicalTrials.gov registry record · Phase 2

Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis

A Phase 2 study, sponsored by Aclaris Therapeutics.

Completed
Registry status
Phase 2
Development phase
172
Enrollment target

NCT02160626: Completed Phase 2 study, sponsored by Aclaris Therapeutics.

NCT02160626 is a Phase 2 study that has completed, run by Aclaris Therapeutics. The registered enrollment target is 172 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02160626, a Phase 2 study, has completed, sponsored by Aclaris Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
172 participants
Enrollment target

Study Summary

The main objective of this study is to evaluate the dose-response relationship of two concentrations of A-101 solution when applied to individual seborrheic keratosis (SK) lesions (target lesions) compared with a matching A-101 Solution Vehicle.

Primary Outcome

Mean of per-subject percentages of target lesions judged to be clear on the PLA (PLA = 0) at end of study (Visit 8). The PLA is a four point scale from 0 being clear to 3 being most severe lesion.

Interventions

  • DRUG A-101 Vehicle
  • DRUG A-101 (40) Topical Solution
  • DRUG A-101 (32.5) Topical Solution

Trial Details

FieldValue
Enrollment Target 172 participants
Start Date 2014-06
Est. Completion 2014-12
Phase Phase 2
Aclaris Therapeutics

33 total trials

What the finished NCT02160626 record still lists

NCT02160626 is an interventional study that assigns participants to a tested intervention. The registered 172 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher).

The record links to 0 conditions, and to 3 interventions - of which A-101 Vehicle is the first listed.

NCT02160626 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02160626 about?

NCT02160626 is a clinical study titled "Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis". The main objective of this study is to evaluate the dose-response relationship of two concentrations of A-101 solution when applied to individual seborrheic keratosis (SK) lesions (target lesions) compared with a matching A-101 Solution Vehicle.

What is the current status of trial NCT02160626?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2014-06. Estimated completion is 2014-12.

What interventions are being tested in trial NCT02160626?

The interventions under investigation include: A-101 Vehicle (DRUG), A-101 (40) Topical Solution (DRUG), A-101 (32.5) Topical Solution (DRUG).

Who is sponsoring clinical trial NCT02160626?

This trial is sponsored by Aclaris Therapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02160626's enrollment target sits among peer trials

172 397th of 2000 higher than 1,603 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02160626, the US trial registry maintained by the National Library of Medicine. NCT02160626 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.