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NCT02260180 · ClinicalTrials.gov registry record · Phase 2

Study of A-101 for the Treatment of Seborrheic Keratosis

A Phase 2 study, sponsored by Aclaris Therapeutics.

Completed
Registry status
Phase 2
Development phase
119
Enrollment target

NCT02260180: Completed Phase 2 study, sponsored by Aclaris Therapeutics.

NCT02260180 is a Phase 2 study that has completed, run by Aclaris Therapeutics. The registered enrollment target is 119 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (11% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02260180, a Phase 2 study, has completed, sponsored by Aclaris Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
119 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and dose-response of 2 concentrations of A-101 versus a vehicle control in the treatment of seborrheic keratosis.

Primary Outcome

The primary effectiveness analysis was a comparison between each A-101 group and the vehicle group based on the percentage with target lesions judged to be clear on the PLA (PLA = 0) at Visit 8. The three arms of the study are A-101 40% Topical Solution, A-101 32.5% Topical Solution, and A-101 0% Topical Solution (vehicle). The Physician's Lesion Analysis ( PLA) is a 4 point scale from 0 to 3, with 0 being lesion clear and 3 being the most severe lesion. A larger proportion of subjects with a PL

Interventions

  • DRUG A-101

Trial Details

FieldValue
Enrollment Target 119 participants
Start Date 2014-10
Est. Completion 2015-03
Phase Phase 2
Aclaris Therapeutics

33 total trials

What the finished NCT02260180 record still lists

NCT02260180 is an interventional study that assigns participants to a tested intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (11% lower).

The record links to 0 conditions, and to 1 intervention - of which A-101 is the first listed.

NCT02260180 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02260180 about?

NCT02260180 is a clinical study titled "Study of A-101 for the Treatment of Seborrheic Keratosis". The purpose of this study is to evaluate the safety and dose-response of 2 concentrations of A-101 versus a vehicle control in the treatment of seborrheic keratosis.

What is the current status of trial NCT02260180?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 119 participants. The study started on 2014-10. Estimated completion is 2015-03.

What interventions are being tested in trial NCT02260180?

The interventions under investigation include: A-101 (DRUG).

Who is sponsoring clinical trial NCT02260180?

This trial is sponsored by Aclaris Therapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02260180's enrollment target sits among peer trials

119 618th of 2000 higher than 1,383 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02260180, the US trial registry maintained by the National Library of Medicine. NCT02260180 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.