Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Urea Cycle Disorder: later-stage trial registry
3 of 5 indexed Urea Cycle Disorder trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #3,391 of 28,707 conditions by registered trial count.
5 US clinical trials · 3 currently recruiting · #3,391 of 28,707 conditions by registered trial count
Urea Cycle Disorder: 5 US clinical trials tracked, 3 recruiting.
Urea Cycle Disorder is the subject of 5 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 3 of these trials.
Enrollment posture brief
Registry condition urea-cycle-disorder
OPEN 3 | RECR 60% | LATE 1 | EARLY 0 | RANK #3391 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Acute Kidney Injury (AKI) (60% recruiting · 5 trials)
Urea Cycle Disorder lists 3 open slots (60% of 5 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Urea Cycle Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Urea Cycle Disorder is recruiting above its size-band peers.
3 of 5 indexed trials (60%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Urea Cycle Disorder research.
Baylor College of Medicine accounts for 3 of 5 trials (60%). 3 distinct sponsors appear on at least one study for this condition label.
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Most Urea Cycle Disorder trials plan to enrol fewer than 100 people.
Median target enrolment is 27 among the 5 trials that report a genuine target (sentinel values excluded). 5 of those (100%) plan for fewer than 100 participants.
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Urea Cycle Disorder research leans observational.
2 interventional and 3 observational studies make up this index (40% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
5 total, page 1 of 1
Hepatic Histopathology in Urea Cycle Disorders
Baylor College of Medicine
NCT04908319
Liver Disease in Urea Cycle Disorders
Baylor College of Medicine
NCT04612764
Systemic Biomarkers of Brain Injury From Hyperammonemia
Children's National Research Institute
NCT04602325
A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders
Amgen
NCT02246218
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD
Baylor College of Medicine
NCT03064048
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Urea Cycle Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Urea Cycle Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Urea Cycle Disorder page
5 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Urea Cycle Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Baylor College of Medicine sponsors the most Urea Cycle Disorder trials on record, review their full trial history before evaluating a specific study. See Baylor College of Medicine's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Urea Cycle Disorder condition card totals 5 registered trials; most-linked intervention RAVICTI; top US site state District of Columbia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.