Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Trigeminal Neuralgia: early-phase trial registry
5 of 10 indexed Trigeminal Neuralgia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 5 currently recruiting · #1,724 of 28,707 conditions by registered trial count
Trigeminal Neuralgia: 10 US clinical trials tracked, 5 recruiting.
Trigeminal Neuralgia is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 2 of these trials.
Enrollment posture brief
Registry condition trigeminal-neuralgia
OPEN 5 | RECR 50% | LATE 1 | EARLY 3 | RANK #1724 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Trigeminal Neuralgia lists 5 open slots (50% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Trigeminal Neuralgia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Trigeminal Neuralgia is recruiting above its size-band peers.
5 of 10 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Trigeminal Neuralgia research.
University of Minnesota accounts for 2 of 10 trials (20%). 9 distinct sponsors appear on at least one study for this condition label.
-
Most Trigeminal Neuralgia trials plan to enrol fewer than 100 people.
Median target enrolment is 40 among the 10 trials that report a genuine target (sentinel values excluded). 6 of those (60%) plan for fewer than 100 participants.
-
Trigeminal Neuralgia research is mostly interventional.
7 interventional and 3 observational studies make up this index (70% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
The Radiosurgery Society
NCT01885299
The Will Erwin Headache Research Center - Cluster Headache Study
The University of Texas Health Science Center, Houston
NCT02910323
Trigeminal Evoked Responses to Improve Rhizotomy
University of Minnesota
NCT05738096
Trigeminal Neuralgia Electrophysiology
University of Minnesota
NCT05269472
OnabotulinumtoxinA for Trigeminal Neuralgia
Stanford University
NCT06216886
An Efficacy and Safety Study of Basimglurant (NOE-101) in Patients With Trigeminal Neuralgia.
Noema Pharma
NCT05217628
RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia Radiosurgery
University of Alabama at Birmingham
NCT02708810
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
University of California, San Francisco
NCT05593237
MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia
University of Maryland, Baltimore
NCT04579692
Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain
National Institute of Dental and Craniofacial Research (NIDCR)
NCT00001725
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Trigeminal Neuralgia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Trigeminal Neuralgia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Trigeminal Neuralgia page
10 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Trigeminal Neuralgia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Minnesota sponsors the most Trigeminal Neuralgia trials on record, review their full trial history before evaluating a specific study. See University of Minnesota's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Trigeminal Neuralgia condition card totals 10 registered trials; most-linked intervention Basimglurant; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.