Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 7 recruiting now early-phase tilt small index

T-cell Acute Lymphoblastic Leukemia: early-phase trial registry

7 of 7 indexed T-cell Acute Lymphoblastic Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,497 of 28,707 conditions by registered trial count.

7 US clinical trials · 7 currently recruiting · #2,497 of 28,707 conditions by registered trial count

T-cell Acute Lymphoblastic Leukemia: 7 US clinical trials tracked, 7 recruiting.

T-cell Acute Lymphoblastic Leukemia is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 2 of these trials.

Enrollment posture brief

Registry condition t-cell-acute-lymphoblastic-leukemia

OPEN 7 | RECR 100% | LATE 0 | EARLY 7 | RANK #2497 | SPON 2

Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)

T-cell Acute Lymphoblast (th…100%ACL Tear71.4%ACL57.1%Acute Myelogenous Leukemia42.9%Acne Scars28.6%
Open-enrollment share among volume-matched conditions near T-cell Acute Lymphoblastic Leukemia

T-cell Acute Lymphoblastic Leukemia lists 7 open slots (100% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for T-cell Acute Lymphoblastic Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. T-cell Acute Lymphoblastic Leukemia is recruiting above its size-band peers.

    7 of 7 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates T-cell Acute Lymphoblastic Leukemia research.

    Baylor College of Medicine accounts for 2 of 7 trials (28.6%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Most T-cell Acute Lymphoblastic Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 7 trials that report a genuine target (sentinel values excluded). 5 of those (71.4%) plan for fewer than 100 participants.

  4. T-cell Acute Lymphoblastic Leukemia research is mostly interventional.

    7 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 24

Open and recent trials

7 total, page 1 of 1

RECRUITING Phase 2 125 participants

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

Wugen

NCT06514794

RECRUITING Phase 2 100 participants

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

St. Jude Children's Research Hospital

NCT06390319

RECRUITING Phase 1 54 participants

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

Baylor College of Medicine

NCT03081910

RECRUITING Phase 1 30 participants

Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA with High Risk T-Cell ALL & Lymphoma

New York Medical College

NCT04972942

RECRUITING Phase 1 27 participants

Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells

Baylor College of Medicine

NCT03690011

RECRUITING Phase 2 22 participants

A Phase 2 Study to Evaluate Efficacy of Calaspargase Pegol-mknl and Decitabine Combined With Venetoclax in Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL) and T- Cell Lymphoblastic Lymphoma (T-LLy)

M.D. Anderson Cancer Center

NCT06561074

RECRUITING Phase 2 20 participants

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

Eastern Cooperative Oncology Group

NCT05289687

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 4

Named interventions

Most-linked intervention names on T-cell Acute Lymphoblastic Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

CD7.CAR/28zeta CAR T cells Genetic
1 trials
Calaspargase pegol-mknl Drug
1 trials
Allogeneic CD5.CAR/28zeta CAR T cells Genetic
1 trials
Autologous CD5.CAR/28zeta CAR T cells Genetic
1 trials
Daratumumab / Hyaluronidase Injection Drug
1 trials
Calaspargase pegol Drug
1 trials
WU-CART-007 Biological
1 trials
Dasatinib Drug
1 trials

US sites by state

Facility locations filed on T-cell Acute Lymphoblastic Leukemia trials. A trial with sites in several states counts in each.

Texas 5 trials
California 3 trials
Pennsylvania 2 trials
Ohio 2 trials
Florida 2 trials
Wisconsin 1 trials
Washington 1 trials
Tennessee 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this T-cell Acute Lymphoblastic Leukemia page

7 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 T-cell Acute Lymphoblastic Leukemia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Baylor College of Medicine sponsors the most T-cell Acute Lymphoblastic Leukemia trials on record, review their full trial history before evaluating a specific study. See Baylor College of Medicine's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This T-cell Acute Lymphoblastic Leukemia condition card totals 7 registered trials; most-linked intervention CD7.CAR/28zeta CAR T cells; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.