Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Symptoms and Signs: early-phase trial registry
3 of 7 indexed Symptoms and Signs trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 3 currently recruiting · #2,497 of 28,707 conditions by registered trial count
Symptoms and Signs: 7 US clinical trials tracked, 3 recruiting.
Symptoms and Signs is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is 4YouandMe, running 1 of these trials.
Enrollment posture brief
Registry condition symptoms-and-signs
OPEN 3 | RECR 43% | LATE 0 | EARLY 1 | RANK #2497 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adrenoleukodystrophy (43% recruiting · 7 trials)
Symptoms and Signs lists 3 open slots (43% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Symptoms and Signs on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Symptoms and Signs is recruiting below its size-band peers.
3 of 7 indexed trials (42.9%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Symptoms and Signs trials is spread across many organizations.
4YouandMe accounts for 1 of 7 trials (14.3%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Symptoms and Signs enrolment sits around 110 participants.
Median target enrolment is 110 among the 7 trials that report a genuine target (sentinel values excluded). 3 of those (42.9%) plan for fewer than 100 participants.
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Symptoms and Signs research is mostly interventional.
5 interventional and 2 observational studies make up this index (71.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer
Virginia Commonwealth University
NCT05958316
Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease
University of Pennsylvania
NCT06136221
Symptom Care at Home-Heart Failure
Emory University
NCT04347759
Confirm Rx Insertable Cardiac Monitor SMART Registry
Abbott Medical Devices
NCT03505801
Implementation Strategies for Monitoring Adherence in Real Time
Abramson Cancer Center at Penn Medicine
NCT04347161
CZI Rare As One: Co-designing an App and Wearable Based Compass for Rare Diseases
4YouandMe
NCT06907953
Title: Leveraging Technology to Address Health Outcomes of Cancer Survivors
University of Maryland, Baltimore
NCT05499663
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Symptoms and Signs records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Symptoms and Signs trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Symptoms and Signs page
7 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Symptoms and Signs trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- 4YouandMe sponsors the most Symptoms and Signs trials on record, review their full trial history before evaluating a specific study. See 4YouandMe's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Symptoms and Signs condition card totals 7 registered trials; most-linked intervention Observational - no intervention; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.