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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Stage III Bladder Cancer AJCC v8: early-phase trial registry

4 of 7 indexed Stage III Bladder Cancer AJCC v8 trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,497 of 28,707 conditions by registered trial count.

7 US clinical trials · 4 currently recruiting · #2,497 of 28,707 conditions by registered trial count

Stage III Bladder Cancer AJCC v8: 7 US clinical trials tracked, 4 recruiting.

Stage III Bladder Cancer AJCC v8 is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 4 of these trials.

Enrollment posture brief

Registry condition stage-iii-bladder-cancer-ajcc-v8

OPEN 4 | RECR 57% | LATE 2 | EARLY 4 | RANK #2497 | SPON 4

Nearest open-share peer: Adverse Childhood Experiences (57% recruiting · 14 trials)

ACL Tear71.4%ACL57.1%Stage III Bladder Cancer (th…57%Acute Myelogenous Leukemia42.9%Acne Scars28.6%
Open-enrollment share among volume-matched conditions near Stage III Bladder Cancer AJCC v8

Stage III Bladder Cancer AJCC v8 lists 4 open slots (57% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage III Bladder Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage III Bladder Cancer AJCC v8 is recruiting above its size-band peers.

    4 of 7 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage III Bladder Cancer AJCC v8 research.

    National Cancer Institute (NCI) accounts for 4 of 7 trials (57.1%). 4 distinct sponsors appear on at least one study for this condition label.

  3. Most Stage III Bladder Cancer AJCC v8 trials plan to enrol fewer than 100 people.

    Median target enrolment is 75 among the 7 trials that report a genuine target (sentinel values excluded). 5 of those (71.4%) plan for fewer than 100 participants.

  4. Stage III Bladder Cancer AJCC v8 research is mostly interventional.

    7 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23Phase 31Phase 41

Open and recent trials

7 total, page 1 of 1

RECRUITING NA 160 participants

An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers

Roswell Park Cancer Institute

NCT06414317

RECRUITING Phase 4 75 participants

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

Mayo Clinic

NCT06764095

RECRUITING Phase 2 60 participants

Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes

National Cancer Institute (NCI)

NCT03375307

RECRUITING Phase 2 25 participants

Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology

Emory University

NCT05756569

ACTIVE NOT RECRUITING Phase 3 654 participants

Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study

National Cancer Institute (NCI)

NCT05092958

ACTIVE NOT RECRUITING Phase 2 95 participants

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

National Cancer Institute (NCI)

NCT04216290

ACTIVE NOT RECRUITING Phase 1 30 participants

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

National Cancer Institute (NCI)

NCT03854474

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Stage III Bladder Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
6 trials
Biospecimen Collection Procedure
6 trials
Bone Scan Procedure
2 trials
Magnetic Resonance Imaging Procedure
2 trials
Enfortumab Vedotin Drug
2 trials
Pembrolizumab Biological
2 trials
Nutritional Assessment Other
1 trials
Consultation Visit Other
1 trials

US sites by state

Facility locations filed on Stage III Bladder Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 3 trials
New York 2 trials
Florida 2 trials
Delaware 2 trials
Colorado 2 trials
Arizona 2 trials
Utah 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage III Bladder Cancer AJCC v8 page

7 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage III Bladder Cancer AJCC v8 condition card totals 7 registered trials; most-linked intervention Computed Tomography; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.