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ClinicalTrials.gov 7 recruiting now later-stage tilt small index

Smoking Reduction: later-stage trial registry

7 of 11 indexed Smoking Reduction trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 7 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Smoking Reduction: 11 US clinical trials tracked, 7 recruiting.

Smoking Reduction is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 2 of these trials.

Enrollment posture brief

Registry condition smoking-reduction

OPEN 7 | RECR 64% | LATE 2 | EARLY 0 | RANK #1577 | SPON 2

Nearest open-share peer: Advanced Melanoma (64% recruiting · 22 trials)

Acute Pancreatitis81.8%Smoking Reduction (this)64%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Smoking Reduction

Smoking Reduction lists 7 open slots (64% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Smoking Reduction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Smoking Reduction is recruiting above its size-band peers.

    7 of 11 indexed trials (63.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Smoking Reduction research.

    University of California, San Francisco accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Smoking Reduction enrolment sits around 83 participants.

    Median target enrolment is 83 among the 11 trials that report a genuine target (sentinel values excluded). 6 of those (54.5%) plan for fewer than 100 participants.

  4. Smoking Reduction research is mostly interventional.

    11 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 31Phase 41

Open and recent trials

11 total, page 1 of 1

RECRUITING NA 800 participants

The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers

Nikki Nollen, PhD, MA

NCT05555069

RECRUITING NA 768 participants

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

University of Virginia

NCT05660525

RECRUITING Phase 3 500 participants

Switching to E-cigarettes in Smokers Not Interested in Quitting

University of Kansas Medical Center

NCT05703672

RECRUITING Phase 4 279 participants

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

University of Minnesota

NCT04783857

RECRUITING NA 20 participants

Trauma-Informed Care for Smoking Cessation for Pregnancy

University of California, San Francisco

NCT07129590

RECRUITING NA 20 participants

rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings

West Virginia University

NCT06228235

RECRUITING NA 10 participants

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

Memorial Sloan Kettering Cancer Center

NCT06693700

ACTIVE NOT RECRUITING NA 300 participants

Construal Level as a Novel Pathway for Affect Regulation and Cancer Control

University of Oregon

NCT04620915

COMPLETED NA 83 participants

Contingency Management for Smoking Cessation

University of California, San Francisco

NCT04982952

COMPLETED NA 80 participants

Feasibility and Efficacy of a Brief Mindfulness-Based Intervention SMOKING INTERVENTION VIA THE INTERNET

Wayne State University

NCT04572126

COMPLETED NA 18 participants

Tobacco Cessation in Public Housing

Johns Hopkins University

NCT04889638

Phase Distribution

PhaseTrial count
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Smoking Reduction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fixed payments Behavioral
1 trials
Contingency Management - Increasing Behavioral
1 trials
Cessation Intervention Other
1 trials
Up-regulation of goal energization Behavioral
1 trials
Down-regulation of craving for cigarettes Behavioral
1 trials
High-level construal Behavioral
1 trials
Indoor Air Quality Monitor AirGradient ONE Other
1 trials
Expired carbon monoxide (CO) Other
1 trials

US sites by state

Facility locations filed on Smoking Reduction trials. A trial with sites in several states counts in each.

Missouri 2 trials
California 2 trials
West Virginia 1 trials
Virginia 1 trials
Oregon 1 trials
New York 1 trials
New Jersey 1 trials
Minnesota 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Smoking Reduction page

11 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Smoking Reduction condition card totals 11 registered trials; most-linked intervention Fixed payments; top US site state Missouri. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.